[18F]-D3FSP(P16-129,D3-AV45):A new imaging agent of β- amyloid in the brain(IND # 137713)

[18F]-D3FSP (P16-129,D3-AV45):A new imaging agent of β- amyloid in the brain

[18F]-D3FSP (P16-129,D3-AV45):A new imaging agent of β- amyloid in the brain

3.Wong, Dean, Hiroto Kuwabara, Kelly Kitzmiller, Ayon Nandi, Zabecca Brinson, Noble George, David Alexoff et al.

 "Comparison of [18F] D3FSP ([18F] P16-129) and [18F] AV45 in Alzheimer’s Disease."Journal of Nuclear Medicine 60, no. supplement 1 (2019): 1457

[18F]-D3FSP β-amyloid PET Imaging in Alzheimer's Disease." Journal of Nuclear MedicineJune 2024,65(supplement 2)241105

[18F]-D3FSP (P16-129,D3-AV45):A new imaging agent of β- amyloid in the brain

[18F]-D3FSP (P16-129,D3-AV45):A new imaging agent of β- amyloid in the brain

广医一院核医学科视频号(转载)
https://mp.weixin.qq.com/s/acWs2yF0J5wqLah0hpmrIA

🌹AD显像药物[18F] D3FSP ([18F] P16-129) Vs [18F]AV-45

Publications:

  1. Li A, Zhao R, Zhang M, Sun P, Cai Y, Zhu L, Kung H, Han Y, Wang X, Guo T. [18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease. European Journal of Nuclear Medicine and Molecular Imaging.51(2024):2794–2805

  2. Li, Anqi, Ruiyue Zhao, Mingkai Zhang, Pan Sun, Yue Cai, Lin Zhu, Hank F. Kung, Ying Han, Xinlu Wang, and Tengfei Guo. "[18F]-D3FSP β-amyloid PET Imaging in Alzheimer's Disease." Journal of Nuclear MedicineJune 2024,65(supplement 2)241105

  3. Li A, Zhao R, Zhang M, Sun P, Cai Y, Liu L, Lan G, Zhu Y, Chen X, Guo L, Zhou Y. [18F]D3FSP amyloid‐β PET imaging in elderly adults and Alzheimer’s disease. Alzheimer's & Dementia. 2023 Dec;19:e079352.
  4. Zha Z, Ploessl K, Choi SR, Alexoff D, Kung HF*. Preclinical evaluation of [18F] D3FSP, deuterated AV-45, for imaging of β-amyloid in the brain. Nuclear medicine and biology. 2021 Jan 1;92:97-106
  5. Zhang L, Zhang A, Yao X, Zhang Y, Liu F, Hong H, Zha Z, Liu Y, Wu Z, Qiao J, Zhu L.“An Improved Preparation of [18F]AV-45 by Simplified Solid-Phase Extraction Purification.” Journal of labelled compounds & radiopharmaceuticals. 63.3 (2020): 108–118.
  6. Wong, Dean, Hiroto Kuwabara, Kelly Kitzmiller, Ayon Nandi, Zabecca Brinson, Noble George, David Alexoff et al. "Comparison of [18F] D3FSP ([18F] P16-129) and [18F] AV45 in Alzheimer’s Disease."Journal of Nuclear Medicine 60, no. supplement 1 (2019): 1457
  7. Yao X, Zha Z, Zhao R, Choi SR, Ploessl K, Liu F, Zhu L, Kung HF. Optimization of solid-phase extraction (SPE) in the preparation of [18F] D3FSP: A new PET imaging agent for mapping Aβ plaques. Nuclear Medicine and Biology. 2019 Apr 1;71:54-64.
  8. Zha, Zhihao, Karl Ploessl, David Alexoff, Seok Choi, Zehui Wu, Lin Zhu, and Hank Kung. "[18F] D3FSP ([18F] D3AV-45) as a PET imaging agent for Abeta plaques in the brain." Journal of Nuclear Medicine 59, no. supplement 1 (2018): 1031
  9. Liu Y, Zhu L, Plössl K, Choi SR, Qiao H, Sun X, Li S, Zha Z, Kung HF. "Optimization of automated radiosynthesis of [18F] AV-45: a new PET imaging agent for Alzheimer's disease." Nuclear medicine and biology 37, no. 8 (2010): 917-925.
  10. Xiao, Hao, Seok Rye Choi, Ruiyue Zhao, Karl Ploessl, David Alexoff, Lin Zhu, Zhihao Zha, and Hank F. Kung. "A new highly deuterated [18F] AV-45,[18F] D15FSP, for imaging β-Amyloid plaques in the brain." ACS Medicinal Chemistry Letters 12, no. 7 (2021): 1086-1092.
  11. Xinyue Yao, Ruiyue Zhao, Zhihao Zha, Seok Choi, Karl Ploessl, David Alexoff, Lin Zhu and Hank Kung. Optimization of solid phase extraction (SPE) in preparation of D3-[18F]FSP: A new PET imaging agent for mapping Aβ plaques.Journal of Nuclear Medicine May 2019, 60 (supplement 1) 485
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