HANK & LIN'S GROUP
The past is prologue and the future is scintillating
1989
1. ALAVI, A., H. KUNG, MP KUNG, S. PAN, J. BILLINGS, R. KASLIWAL, M. REIVICH, and J. REILLEY. "Division of Nuclear Medicine, Department of Radiology, Cerebrovascular Research Center, Department of Neurology, Hospital of the University of Pennsylvania, 34OO Spruce Street, Philadelphia, PA USA." In Cerebral Vascular Disease 7: Proceedings of the World Federation of Neurology 14th International Salzberg Conference, September 28-October 1, 1988, p. 135. Elsevier, 1989.
2. Bergsland, J., E. A. Carr Jr, M. Carroll, M. J. Feldman, H. Kung, and J. R. Wright. "Uptake of perfusion imaging agents by transplanted hearts: an experimental study in rats." Journal of Surgical Research 46, no. 2 (1989): 184-186.
3. Billings J, Kung MP, Chumpradit S, Pan S, Kung HF. [125I](+/-)FISCH: a new CNS D-1 dopamine receptor imaging ligand. Life Sci. 1989;45(8):711-8. doi: 10.1016/0024-3205(89)90090-8. PMID: 2779358.
4. Chumpradit S, Kung HF, Billings J, Guo YZ, Wu Y, Shih J. Preparation and biodistribution of 1-[2-(3-[125I]iodo-4-aminophenyl)ethyl]-4-[3-(trifluoromethyl) phenyl]piperazine and 1-[2-(3-[125I]iodo-4-azidophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl] piperazine. J Med Chem. 1989 Mar;32(3):543-7. doi: 10.1021/jm00123a006. PMID: 2918500.
5. Chumpradit S, Kung HF, Billings J, Kung MP, Pan S. (+/-)-7-chloro-8-hydroxy-1-(4'-[125I]iodophenyl)-3-methyl-2,3,4,5- tetrahydro-1H-3-benzazepine: a potential CNS D-1 dopamine receptor imaging agent. J Med Chem. 1989 Jul;32(7):1431-5. doi: 10.1021/jm00127a005. PMID: 2525621.
6. Chumpradit, S., H. F. Kung, J. Billings, Y. Z. Guo, Y. Wu, and J. Shih. "Preparation and biodistribution of 1-(2-(3-(/sup 125/I) iodo-4-aminophenyl) ethyl)-4-(3-(trifluoromethyl) phenyl) piperazine and 1-(2-(3-(/sup 125/I) iodo-4-azidophenyl) ethyl)-4-(3-(trifluoromethyl) phenyl) piperazine." J. Med. Chem.;(United States) 32, no. 3 (1989).
7. Efange SM, Mash D, Hefti F, Kung HF, Billings J. Selective visualization of rodent locus ceruleus by a radiolabeled N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analog. J Neurochem. 1989 Aug;53(2):459-64. doi: 10.1111/j.1471-4159.1989.tb07356.x. PMID: 2787390.
8. Eisen, H. J., R. G. Nader, J. Reilly, T. Nguyen, J. Billings, A. ByaR, H. Kung, and A. Alavi. "Assessment of regional myocardial adrenergic activity following myocardial infarction using I-123 metaiodobenzylguanidine." Circulation 80, no. suppl (1989): II-514.
9. Kung HF, Pan S, Kung MP, Billings J, Kasliwal R, Reilley J, Alavi A. In vitro and in vivo evaluation of [123I]IBZM: a potential CNS D-2 dopamine receptor imaging agent. J Nucl Med. 1989 Jan;30(1):88-92. PMID: 2783457.
10. Kung HF, Guo YZ, Yu CC, Billings J, Subramanyam V, Calabrese JC. New brain perfusion imaging agents based on 99mTc-bis(aminoethanethiol) complexes: stereoisomers and biodistribution. J Med Chem. 1989 Feb;32(2):433-7. doi: 10.1021/jm00122a024. PMID: 2913304.
11. Kung, Hank F., Bo-Li Liu, and Sangren Pan. "Kinetic study of ligand exchange reaction between 99mTc-glucoheptonate and N-benzyl-N-methyl-piperazinyl-bis-(aminoethanethiol)(BPA-BAT)." International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes 40, no. 8 (1989): 677-681.
12. Kung, Mei‐Ping, and Hank F. Kung. "Peracetic acid as a superior oxidant for preparation of [123I] IBZM: A potential dopamine D‐2 receptor imaging agent." Journal of Labelled Compounds and Radiopharmaceuticals 27, no. 6 (1989): 691-700.
13. Liu BL, Kung HF, Jin YT, Zhu L, Meng M. Synthesis, characterization, and biodistribution of [113mIn]TE-BAT: a new myocardial imaging agent. J Nucl Med. 1989 Mar;30(3):367-73. PMID: 2738665.
14. Mach RH, Kung HF, Guo YZ, Yu CC, Subramanyam V, Calabrese JC. Synthesis, characterization and biodistribution of neutral and lipid-soluble 99mTc-PAT-HM and 99mTc-TMR for brain imaging. Int J Rad Appl Instrum B. 1989;16(8):829-37. doi: 10.1016/0883-2897(89)90168-2. PMID: 2621118.
15. Mach, R. H., H. F. Kung, P. Jungwiwattanaporn, and Y-Z. Guo. "A new synthesis of bis-aminoethanethiol (BAT) chelating agents containing a gamma carboxylate." Tetrahedron letters30, no. 31 (1989): 4069-4072.
16. Schonwetter BS, Luedtke RR, Kung MP, Billings J, Kung HF, Molinoff PB. Characterization of membrane-bound and soluble D2 receptors in canine caudate using [125I]IBZM. J Pharmacol Exp Ther. 1989 Jul;250(1):110-6. PMID: 2526213.
17. Velchik, M. G.; Kung, H. F.; Alavi, A.; Kung, M. P.; Chang, W.; Noto, R.; Pan, S.; Billings, J.; Sorgentoni, K.; Rauch, A.; Reilley, J. I-123-IBZM, Clinical Nuclear Medicine: March 1989 - Volume 14 - Issue 3 - p 232
18. Velchik, M. G.; Kung, H. F.; Alavi, A.; Chang, W.; Sorgentoni, K. A BASAL GANGLIA PHANTOM FOR 1–123-IBZM SPECT QUANTITATION, Clinical Nuclear Medicine: March 1989 - Volume 14 - Issue 3 - p 235
19. Lin, Zhu, Boli, Liu, Zhiqiang, Yang, and Kung, H F. The study of a series of sup 113m In-BAT complexes; Biodistribution and the relationships between structure and partition coefficient. China: N. p., 1989. Web.
20. Zhu Lin, Liu Boli, Yang Zhiqiang, & Kung, H.F. (1989). The study of a series of 113mIn-BAT complexes. Journal of Nuclear and Radiochemistry, 11(3), 163-168.
21. Alavi, A., H. Kung, M. P. Kung, S. Pan, J. Billings, R. Kasliwal, M. Reivich, and J. Reilley. "(123 I) IBZM: a potential CNS D-2 dopamine receptor imaging agent." In Cerebral vascular disease 7. 1989.
22. Kung, H. F., Boli Liu, and Sangren Pan. "Kinetic study of ligand exchange reaction between sup 99m Tc-glucoheptonate and N-benzyl-N-methyl-piperazinyl-bis-(aminoethanethiol)(BPA-BAT)." Applied Radiation and Isotopes;(UK) 40, no. 8 (1989).
23. Kung, Hank F. "Brain perfusion imaging with iodinated amines." In New procedures in nuclear medicine. 1989.
24. Kung, H. F., M. P. Kung, S. Pan, R. Kasliwal, J. Billings, and Y-Z. Guo. "Radiolabeling and CNS D-2 dopamine receptor specificity of iodobenzamide (IBZM) and iodolisuride (ILIS)." Journal of Labelled Compounds and Radiopharmaceuticals;(UK) 26, no. pt 1 (1989).
25. Kung, H. F., M. P. Kung, S. Pan, R. Kasliwal, J. Billings, and Y-Z. Guo. "Radiolabeling and CNS D-2 dopamine receptor specificity of iodobenzamide (IBZM) and iodolisuride (ILIS)." Journal of Labelled Compounds and Radiopharmaceuticals;(UK) 26, no. pt 1 (1989).
26. Mach, R. H., H. F. Kung, Yuzhi Guo, Chichou Yu, V. Subramanyam, and J. C. Calabrese. "Synthesis, characterization and biodistribution of neutral and lipid-soluble sup 99m Tc-PAT-HM and sup 99m Tc-TMR for brain imaging." Nuclear Medicine and Biology;(UK) 16, no. 8 (1989).
1988
1. Brücke T, Tsai YF, McLellan C, Singhanyom W, Kung HF, Cohen RM, Chiueh CC. In vitro binding properties and autoradiographic imaging of 3-iodobenzamide ([125I]-IBZM): a potential imaging ligand for D-2 dopamine receptors in SPECT. Life Sci. 1988;42(21):2097-104. doi: 10.1016/0024-3205(88)90123-3. PMID: 3260318.
2. Chiueh, C. C., R. M. Cohen, K. L. Kirk, R. D. Finn, G. Firnau, and H. F. Kung. "Imaging of pre-and post-synaptic adaptations in the nigrostriatal dopaminergic system of MPTP-induced parkinsonism." In Pharmacology and Functional Regulation of Dopaminergic Neurons, pp. 329-335. Palgrave Macmillan, London, 1988.
3. Drayer BP, Albright R, Jaszczak RJ, Velaj R, Kung HF, Greer KL, Coleman RE. Single-photon-emission computed tomographic imaging of glioma. Am J Physiol Imaging. 1988;3(1):57-8. PMID: 3260506.
4. Efange SM, Kung HF, Billings JJ, Blau M. Synthesis and biodistribution of 99mTc-labeled piperidinyl bis(aminoethanethiol) complexes: potential brain perfusion imaging agents for single photon emission computed tomography. J Med Chem. 1988 May;31(5):1043-7. doi: 10.1021/jm00400a028. PMID: 3258924.
5. Karatzas ND, Sfakianakis GN, Pappas D, Duncan R, Heal A, Serafini A, Kung HF. Experimental increase in brain HIPDM uptake by hypercapnia. J Nucl Med. 1988 Oct;29(10):1675-82. PMID: 3262727.
6. Kostyniak PJ, Brenner JS, Maccubbin AE, Nakeeb S, Kasliwal R, Kung HF. The toxicity and mutagenicity of S-3-iodo-N-(1-ethyl-2-pyrrolidinyl)methyl-2-hydroxy-6-methoxybenzamide (IBZM), a new CNS D-2 dopamine receptor imaging agent. Drug Chem Toxicol. 1988;11(4):433-42. doi: 10.3109/01480548809018113. PMID: 2977324.
7. Kung HF, Kasliwal R, Pan SG, Kung MP, Mach RH, Guo YZ. Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide. J Med Chem. 1988 May;31(5):1039-43. doi: 10.1021/jm00400a027. PMID: 2966245.
8. Kung HF, Billings JJ, Guo YZ, Blau M, Ackerhalt R. Preparation and biodistribution of [125I]IBZP: a potential CNS D-1 dopamine receptor imaging agent. Int J Rad Appl Instrum B. 1988;15(2):187-93. doi: 10.1016/0883-2897(88)90087-6. PMID: 2966781.
9. Kung HF, Guo YZ, Billings J, Xu X, Mach RH, Blau M, Ackerhalt RE. Preparation and biodistribution of [125I]IBZM: a potential CNS D-2 dopamine receptor imaging agent. Int J Rad Appl Instrum B. 1988;15(2):195-201. doi: 10.1016/0883-2897(88)90088-8. PMID: 2966782.
10. Kung HF, Billings JJ, Guo YZ, Mach RH. Comparison of in vivo D-2 dopamine receptor binding of IBZM and NMSP in rat brain. Int J Rad Appl Instrum B. 1988;15(2):203-8. doi: 10.1016/0883-2897(88)90089-x. PMID: 2966783.
11. Kung HF, Billings J, Farrell E, Blau M. Effect of anesthetics on the uptake of brain imaging agents in rats. Am J Physiol Imaging. 1988;3(1):36. PMID: 3390354.
12. Liu, Boli, Yutai Jin, Lin Zhu, Min Meng, Yajun Shi, and H. F. Kung. "Study of a new myocardial imaging agent--113m In-BAT-TE." Journal of Nuclear and Radiochemistry 10, no. 3 (1988): 162-168.
13. Shih WJ, Coupal JJ, Dillon ML, Kung HF. Application of I-123 HIPDM as a lung imaging agent. Eur J Nucl Med. 1988;14(1):21-4. doi: 10.1007/BF00252612. PMID: 3383904.
14. Singhaniyom W, Tsai YF, Brücke T, McLellan CA, Cohen RM, Kung HF, Chiueh CC. Blockade of in vivo binding of 125I-labeled 3-iodobenzamide (IBZM) to dopamine receptors by D2 antagonist and agonist. Brain Res. 1988 Jun 21;453(1-2):393-6. doi: 10.1016/0006-8993(88)90186-2. PMID: 2969766.
15. Boli, Liu, Jin Yutai, Zhu Lin, Meng Min, Shi Yajun, and H. F. Kung. "Study of a new myocardial imaging agent--/sup 113m/In-BAT-TE." Heh Hua Hsueh Yu Fang She Hua Hsueh;(China) 10, no. 3 (1988).
16. Yuzhi, Guo, H. F. Kung, and R. H. Mack. "Preliminary studies of/sup 99m/Tc labeled fatty acid analogs for myocardial imaging." Heh Hua Hsueh Yu Fang She Hua Hsueh;(China)10, no. 4 (1988).
17. Kung, H. F., A. Alavi, J. Billings, M. P. Kung, S. Pan, and J. Reilly. "[123I] IBZP: A potential CNS D-1 dopamine receptor imaging agent: In vivo biodistribution in a monkey." J Nucl Med29 (1988): 758.
18. Kung, H. F., J. Billings, E. Farrell, and M. Blau. "Effect of anesthetics on the uptake of brain imaging agents in rats." American journal of physiologic imaging 3, no. 1 (1988): 36.
19. SCHONWETTER, BS, RR LUEDTKE, HF KUNG, and PB MOLINOFF. "BINDING OF I125 IBZM AND H-3-SPD TO D2 RECEPTORS IN CANINE CAUDATE." In FASEB JOURNAL, vol. 2, no. 4, pp. A365-A365. 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998: FEDERATION AMER SOC EXP BIOL, 1988.
20. Shih, W. J., S. Dekosky, J. J. Coupal, D. Clark, U. Y. Ryo, and H. F. Kung. "Transtentorial diachisis in stroke patients demonstrated by I-123 HIPDM brain imaging." In Radiological Society of North America 74th scientific assembly and annual meeting (Abstracts). 1988.
1987
1. Boyko OB, Park HM, Edwards MK, Wellman HN, Glazier MC, Marquart CL, Kung HF. I-123 HIPDM SPECT imaging and cerebral angiography for EC-IC bypass evaluation. Radiographics. 1987 May;7(3):563-77. doi: 10.1148/radiographics.7.3.3502370. PMID: 3502370.
2. Efange SM, Kung HF, Billings J, Guo YZ, Blau M. Technetium-99m bis (aminoethanethiol) complexes with amine sidechains--potential brain perfusion imaging agents for SPECT. J Nucl Med. 1987 Jun;28(6):1012-9. PMID: 3108466.
3. Lee, B. I., O. N. Markand, H. N. Wellman, A. R. Siddiqui, B. Mock, J. Krepshaw, and Hank Kung. "HIPDM single photon emission computed tomography brain imaging in partial onset secondarily generalized tonic‐clonic seizures." Epilepsia 28, no. 3 (1987): 305-311.
4. Liu B, Chang J, Sun JS, Billings J, Steves A, Ackerhalt R, Molnar M, Kung HF. Radioactive iodine exchange reaction of HIPDM: kinetics and mechanism. J Nucl Med. 1987 Mar;28(3):360-5. PMID: 3819852.
5. Liu, Bo-Li, Hank F. Kung, Jeffrey Billings, and Monte Blau. "Comparison of [28Br] 4-bromoantipyrine and [125I] 4-iodoantipyrine: The kinetics of exchange reaction and biodistribution in rats." International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology 14, no. 1 (1987): 69-74.
6. Moretti JL, Kung HF, Cesaro P, Blau M, Defer G, Holman L, Vigneron N, Rapin JR. Temporal evolution of brain distribution of IMP and HIPDM. Concise communication. Nucl Med Commun. 1987 Jul;8(7):597-602. PMID: 3500438.
7. Shih, W. J., W. R. Markesbery, D. B. Clark, S. Goldstein, P. A. Domstad, J. J. Coupal, H. Kung, S. T. DeKosky, and F. H. DeLand. "Iodine-123 HIPDM brain imaging findings in subacute spongiform encephalopathy (Creutzfeldt-Jakob disease)." Journal of nuclear medicine 28, no. 9 (1987): 1484-1487.
8. Shih, W. J., S. Magoun, J. J. Coupal, D. B. Clark, S. T. Dekosky, H. F. Kung, R. Beihn, and U. Y. Ryo. "Abnormal I-123 HIPDM images in various disease entities." In Radiological Society of North America 73rd scientific assembly and annual meeting (Abstracts). 1987.
1986
1. Kung HF. Labeling of interferons with [35S]methionine in a cell-free DNA-dependent system. Methods Enzymol. 1986;119:292-6. doi: 10.1016/0076-6879(86)19044-6. PMID: 2429146.
2. Kung, Hank F. "Brain radiopharmaceuticals." Radiopharmaceuticals: Progress and Clinical Perspectives 1 (1986): 21-39.
3. Kung, H. F., X-J. Xu, and Y-Z. Guo. "Preparation and radiolabeling of IBZM: a potential D-2 specific brain imaging agents for SPECT." Journal of Labelled Compounds and Radiopharmaceuticals 23, no. 10-12 (1986): 1318-1319.
4. Mach, R. H., H. F. Kung, X-J. Xu, Y-Z. Guo, and M. Blau. "Synthesis and biodistribution of Tc-99m BAT-PDA: a potential heart imaging agent for SPECT." Journal of Labelled Compounds and Radiopharmaceuticals 23, no. 10-12 (1986): 1138-1140.
5. Mathis, C. A., S. M. Moerlein, Y. Yano, A. T. Shulgin, R. N. Hanson, and H. F. Kung. "Rapid labeling of radiopharmaceuticals with iodine-122." Journal of Labelled Compounds and Radiopharmaceuticals 23, no. 10-12 (1986): 1259-1261.
6. BERGSLAND, J., EA CARR, M. CARROLL, H. KUNG, JN BHAYANA, MJ FELDMAN, and JR WRIGHT. "THE UPTAKE OF TC-99M TBI AND T1-201 BY TRANSPLANTED RAT HEARTS." In JOURNAL OF NUCLEAR MEDICINE, vol. 27, no. 6, pp. 966-966. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316: SOC NUCLEAR MEDICINE INC, 1986.
7. Kung, H. F., J. B. Billings, and Y. Z. Guo. "INVIVO BIO DISTRIBUTION OF SKF-103108A-A POTENTIAL D-1 RECEPTOR-SITE SPECIFIC IMAGING AGENT." In JOURNAL OF NUCLEAR MEDICINE, vol. 27, no. 6, pp. 906-906. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316: SOC NUCLEAR MEDICINE INC, 1986.
8. Kung, H. F., Y. Z. Guo, and J. B. Billings. "NEW SEROTONIN RECEPTOR-SITE SPECIFIC BRAIN IMAGING AGENT-RADIOACTIVE IODINATED 8-OH-DPAT." In JOURNAL OF NUCLEAR MEDICINE, vol. 27, no. 6, pp. 972-972. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316: SOC NUCLEAR MEDICINE INC, 1986.
9. Kung, H. F., Y. Z. Guo, C. C. Yu, R. H. Mach, S. M. N. Efange, and M. Blau. "New Tc-99 complexes based on N2S2 ligands." In JOURNAL OF NUCLEAR MEDICINE, vol. 27, no. 6, pp. 1051-1051. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316: SOC NUCLEAR MEDICINE INC, 1986.
1985
1. BILLINGS, JEFFREY, ELONGIA FARRELL, MONTE BLAU, and HANK F. KUNG. "The effect of anaesthetics on the uptake of brain-imaging agents in rats." Nuclear Medicine Communications 6, no. 2 (1985): 83-89.
2. Kung HF, Billings J, Farrell E, Blau M. The effect of anaesthetics on the uptake of brain-imaging agents in rats. Nucl Med Commun. 1985 Feb;6(2):75-81. PMID: 3880119.
3. Kung HF, Yu CC, Billings J, Molnar M, Blau M. Synthesis of new bis(aminoethanethiol) (BAT) derivatives: possible ligands for 99mTc brain imaging agents. J Med Chem. 1985 Sep;28(9):1280-4. doi: 10.1021/jm00147a028. PMID: 2993617.
4. Lucignani, G., F. Fazio, A. Nehlig, R. Blasberg, C. S. Patlak, L. Anderson, H. F. Kung, C. Fieschi, and L. Sokoloff. "Evaluation of [125I] HIPDM as a Potential Tracer for Quantitative Measurement of Regional Cerebral Blood Flow." In Cerebral Blood Flow and Metabolism Measurement, pp. 301-304. Springer, Berlin, Heidelberg, 1985.
5. Lucignani, G., A. Nehlig, R. Blasberg, S. Patlak, L. Anderson, C. Fieschi, F. Fazio, and L. Sokoloff. "Metabolic and kinetic considerations in the use of [125I] HIPDM for quantitative measurement of regional cerebral blood flow." Journal of Cerebral Blood Flow & Metabolism 5, no. 1 (1985): 86-96.
6. Blau, M., and H. F. Kung. Iodine-123-labeled pH shift brain-imaging agents. No. CONF-820523--. 1985.
7. Kung, H. F., S. Efange, C. C. Yu, J. Billings, and M. Blau. "Synthesis and biodistribution of Tc-99m bis-aminoethanethiol (BAT) complexes with amine side chains." Journal of Nuclear Medicine 26, no. 5 (1985): 18
8. KUNG, HANK F. "Iodine-123-Labeled pH Shift Brain-Imaging Agents." The Developing Role of Short-Lived Radionuclides in Nuclear Medical Practice (1985): 320.
9. Liu, B. L., J. Chang, J. S. Sun, J. Billings, M. Blau, and H. F. Kung. "Radioactive iodine exchange reaction of HIPDM: Kinetics and mechanism." Journal of Nuclear Medicine 26, no. 5 (1985): 123.
10. Mathis, C. A., T. F. Budinger, T. Sargent III, A. T. Shulgin, and H. F. Kung. "Generator produced I-122 labeled amines and diamines for brain blood flow measurements in neurologic disorders." Journal of Nuclear Medicine 26, no. 5 (1985): 105.
