HANK & LIN'S GROUP
The past is prologue and the future is scintillating
1999
1. Acton PD, Mu M, Plössl K, Hou C, Siciliano M, Zhuang ZP, Oya S, Choi SR, Kung HF. Single-photon emission tomography imaging of serotonin transporters in the nonhuman primate brain with [(123)I]ODAM. Eur J Nucl Med. 1999 Oct;26(10):1359-62. doi: 10.1007/s002590050596. PMID: 10541838.
2. Acton PD, Pilowsky LS, Kung HF, Ell PJ. Automatic segmentation of dynamic neuroreceptor single-photon emission tomography images using fuzzy clustering. Eur J Nucl Med. 1999 Jun;26(6):581-90. doi: 10.1007/s002590050425. PMID: 10369943.
3. Acton PD, Kushner SA, Kung MP, Mozley PD, Plössl K, Kung HF. Simplified reference region model for the kinetic analysis of [99mTc]TRODAT-1 binding to dopamine transporters in nonhuman primates using single-photon emission tomography. Eur J Nucl Med. 1999 May;26(5):518-26. doi: 10.1007/s002590050420. PMID: 10382097.
4. Acton PD, Kung MP, Mu M, Plössl K, Hou C, Siciliano M, Oya S, Kung HF. Single-photon emission tomography imaging of serotonin transporters in the non-human primate brain with the selective radioligand [(123)I]IDAM. Eur J Nucl Med. 1999 Aug;26(8):854-61. doi: 10.1007/s002590050459. PMID: 10436198.
5. Acton, Paul D., P. David Mozley, and Hank F. Kung. "Logistic discriminant parametric mapping: a novel method for the pixel-based differential diagnosis of Parkinson’s disease." European journal of nuclear medicine 26, no. 11 (1999): 1413-1423.
6. Choi SR, Kung MP, Plössl K, Meegalla S, Kung HF. An improved kit formulation of a dopamine transporter imaging agent: [Tc-99m]TRODAT-1. Nucl Med Biol. 1999 May;26(4):461-6. doi: 10.1016/s0969-8051(99)00010-4. PMID: 10382851.
7. Dresel SH, Kung MP, Huang XF, Plössl K, Hou C, Meegalla SK, Patselas G, Mu M, Saffer JR, Kung HF. Simultaneous SPECT studies of pre- and postsynaptic dopamine binding sites in baboons. J Nucl Med. 1999 Apr;40(4):660-6. PMID: 10210226.
8. Dresel SH, Kung MP, Huang X, Plössl K, Hou C, Shiue CY, Karp J, Kung HF. In vivo imaging of serotonin transporters with [99mTc]TRODAT-1 in nonhuman primates. Eur J Nucl Med. 1999 Apr;26(4):342-7. doi: 10.1007/s002590050396. PMID: 10199939.
9. Kung MP, Hou C, Oya S, Mu M, Acton PD, Kung HF. Characterization of [(123)I]IDAM as a novel single-photon emission tomography tracer for serotonin transporters. Eur J Nucl Med. 1999 Aug;26(8):844-53. doi: 10.1007/s002590050458. PMID: 10436197.
10. Kushner SA, McElgin WT, Kung MP, Mozley PD, Plössl K, Meegalla SK, Mu M, Dresel S, Vessotskie JM, Lexow N, Kung HF. Kinetic modeling of [99mTc]TRODAT-1: a dopamine transporter imaging agent. J Nucl Med. 1999 Jan;40(1):150-8. PMID: 9935071.
11. Mozley PD, Acton PD, Barraclough ED, Plössl K, Gur RC, Alavi A, Mathur A, Saffer J, Kung HF. Effects of age on dopamine transporters in healthy humans. J Nucl Med. 1999 Nov;40(11):1812-7. PMID: 10565775.
12. Mu M, Kung MP, Plössl K, Acton PD, Mozley PD, Kung HF. A simplified method to determine [99mTc]TRODAT-1 in human plasma. Nucl Med Biol. 1999 Oct;26(7):821-5. doi: 10.1016/s0969-8051(99)00065-7. PMID: 10628563.
13. Oya S, Kung MP, Acton PD, Mu M, Hou C, Kung HF. A new single-photon emission computed tomography imaging agent for serotonin transporters: [123I]IDAM, 5-iodo-2-((2-((dimethylamino)methyl)phenyl)thio)benzyl alcohol. J Med Chem. 1999 Feb 11;42(3):333-5. doi: 10.1021/jm9806751. PMID: 9986702.
14. Xu Y, Choi SR, Kung MP, Kung HF. Synthesis of radioiodinated 1-deoxy-nojirimycin derivatives: novel glucose analogs. Nucl Med Biol. 1999 Oct;26(7):833-9. doi: 10.1016/s0969-8051(99)00063-3. PMID: 10628565.
15. Zhuang ZP, Plössl K, Kung MP, Mu M, Kung HF. Neutral and stereospecific Tc-99m complexes: [99mTc]N-benzyl-3,4-di-(N-2-mercaptoethyl)-amino-pyrrolidines (P-BAT). Nucl Med Biol. 1999 Feb;26(2):217-24. doi: 10.1016/s0969-8051(98)00099-7. PMID: 10100222.
16. Zhuang ZP, Kung MP, Mu M, Hou C, Kung HF. 99mTc-labeled MIBG derivatives: novel 99mTc complexes as myocardial imaging agents for sympathetic neurons. Bioconjug Chem. 1999 Mar-Apr;10(2):159-68. doi: 10.1021/bc970207q. PMID: 10077463.
17. Acton, P. D., M. P. Kung, K. Plossl, M. Mu, C. Hou, M. Siciliano, S. Oya, and H. F. Kung. "SPECT imaging of serotonin transporters in the non-human primate brain with the selective tracer [I-123] IDAM." In JOURNAL OF NUCLEAR MEDICINE, vol. 40, no. 5, pp. 306P-306P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1999.
18. Acton, P. D., S. A. Kushner, M. P. Kung, P. D. Mozley, K. Plossl, and H. F. Kung. "Simplified quantification of dopamine transporters using [Tc-99m] TRODAT-1 and SPECT." In JOURNAL OF NUCLEAR MEDICINE, vol. 40, no. 5, pp. 145P-145P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1999.
19. Choi, S. R., Y. M. Xu, M. P. Kung, H. F. Kung, and H. F. Kung. "N-3'-iodobenyl-1-deoxy-norjirimycin as potential tumor imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 40, no. 5, pp. 308P-308P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1999.
20. Chumpradit, S., M. P. Kung, K. Plossl, M. Mu, and H. Kung. "Poster Session M-Neurology-M-7-Design and synthesis of 99m Tc-labeled dopamine D2/D3 receptor imaging agents." Journal of Labelled Compounds and Radiopharmaceuticals42, no. 1 (1999): S354.
21. Krim, L., J. M. Axten, H. F. Kung, and J. D. Winkler. "A stereoselective synthesis of dl-threo-methylphenidate: Preparation and biological evaluation of novel analogs." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 217, pp. U107-U107. 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC, 1999.
22. Kung, H. F., Z. P. Zhuang, M. P. Kung, K. Plossl, C. Hou, P. D. Mozley, P. D. Acton, and M. Mu. "Tc-99m tropane derivatives as dopamine transporter imaging agents." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 217, pp. U56-U56. 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC, 1999.
23. Mozley, P. D., J. S. Schneider, L. M. H. Mozley, R. C. Gur, E. D. Barraclough, K. Plossl, A. Alavi, P. D. Acton, A. Mathur, and H. F. Kung. "[Tc-99m] TRODAT-1 and motor function in patients with Parkinson's disease." In JOURNAL OF NUCLEAR MEDICINE, vol. 40, no. 5, pp. 271P-271P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1999.
24. Mu, M., M. P. Kung, K. Plössl, S. Oya, P. D. Mozley, and H. F. Kung. "Quantitation of [Tc-99m] TRODAT-1 in human plasma samples by a simple extraction method." J Labelled Compd Radiopharm 42 (1999): S213-S215.
25. Oya, S., M. Kung, C. Hou, P. Acton, M. Mu, and H. Kung. "Structure-activity relationship of IDAM and its derivatives as serotonin transporter imaging agents." Journal of Labelled Compounds and Radiopharmaceuticals 42 (1999): S57-S59.
26. Plossl, K., M. P. Kung, S. K. Meegalla, A. Stevenson, M. Mu, and H. F. Kung. "Stereoselectivity and specificity of [Tc-99m] TRODAT-1 derivatives as CNS dopamine transporter imaging agents." In JOURNAL OF NUCLEAR MEDICINE, vol. 40, no. 5, pp. 38P-38P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1999.
27. Szajek, L., H. Kung, P. Plascjak, K. Plossl, P. Acton, P. Herscovitch, and W. Eckelman. "Comparison of [Tc-94m] and [Tc-99m] TRODAT-1 as imaging agents for the dopamine transporter." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 42 (1999): S45-S47.
28. Zhuang, Z. P., S. R. Choi, C. Hou, and H. Kung. "Synthesis of [^ 1^ 2^ 3I] ODAM as a serotonin transporter imaging agent." Journal of Labelled Compounds and Radiopharmaceuticals 42 (1999): S357-S359.
29. Zhuang, Z. P., M. Mu, M. P. Kung, K. Plossl, and H. Kung. "Poster Session M-Neurology-M-6-Homologue of (99mTc) TRODAT-1 as dopamine transporter imaging agent." Journal of Labelled Compounds and Radiopharmaceuticals 42, no. 1 (1999): S351.
1998
1. Axten, Jeffrey M., Lori Krim, Hank F. Kung, and Jeffrey D. Winkler. "A stereoselective synthesis of dl-threo-methylphenidate: preparation and biological evaluation of novel analogues." The Journal of Organic Chemistry 63, no. 26 (1998): 9628-9629.
2. Dresel SH, Kung MP, Plössl K, Meegalla SK, Kung HF. Pharmacological effects of dopaminergic drugs on in vivo binding of [99mTc]TRODAT-1 to the central dopamine transporters in rats. Eur J Nucl Med. 1998 Jan;25(1):31-9. doi: 10.1007/s002590050191. PMID: 9396872.
3. Kung, Hank F., Sanath Meegalla, Mei-Ping Kung, and Karl Plössl. "Development of 99mTc-labelled complexes for imaging dopamine transporters in the brain." Transition Metal Chemistry 23, no. 4 (1998): 531-536.
4. Meegalla SK, Plössl K, Kung MP, Stevenson DA, Mu M, Kushner S, Liable-Sands LM, Rheingold AL, Kung HF. Specificity of diastereomers of [99mTc]TRODAT-1 as dopamine transporter imaging agents. J Med Chem. 1998 Feb 12;41(4):428-36. doi: 10.1021/jm970742b. PMID: 9484494.
5. Mozley PD, Stubbs JB, Plössl K, Dresel SH, Barraclough ED, Alavi A, Araujo LI, Kung HF. Biodistribution and dosimetry of TRODAT-1: a technetium-99m tropane for imaging dopamine transporters. J Nucl Med. 1998 Dec;39(12):2069-76. PMID: 9867143.
6. Oya S, Plössl K, Kung MP, Stevenson DA, Kung HF. Small and neutral Tc(v)O BAT, bisaminoethanethiol (N2S2) complexes for developing new brain imaging agents. Nucl Med Biol. 1998 Feb;25(2):135-40. doi: 10.1016/s0969-8051(97)00153-4. PMID: 9468028.
7. Ramboz, Sylvie, Ronald Oosting, Djamel Aït Amara, Hank F. Kung, Pierre Blier, Monica Mendelsohn, J. John Mann, Dani Brunner, and René Hen. "Serotonin receptor 1A knockout: an animal model of anxiety-related disorder." Proceedings of the National Academy of Sciences 95, no. 24 (1998): 14476-14481.
8. Sukal, Sean, Joseph E. Bradshaw, Jiafang He, Glenn Pa Yap, Arnold L. Rheingold, Hank F. Kung, and Lynn C. Francesconi. "Copper and rhenium complexes of abis (aminoethanethiol) ligand." Polyhedron 18, no. 1-2 (1998): 7-17.
9. Zhuang ZP, Kung MP, Mu M, Kung HF. Isoindol-1-one analogues of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridyl)-p-iodobenzamido]ethyl]pipera zine (p-MPPI) as 5-HT1A receptor ligands. J Med Chem. 1998 Jan 15;41(2):157-66. doi: 10.1021/jm970296s. PMID: 9457239.
10. Choi, S. R., M. P. Kung, K. Plossl, S. K. Meegalla, and H. F. Kung. "An improved kit formulation of [Tc-99m] TRODAT-1 as a dopamine transporter imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 39, no. 5, pp. 220P-220P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1998.
11. Dresel, S., X. F. Huang, K. Plossl, S. K. Meegalla, G. Patselas, M. Mu, J. Saffer, and H. F. Kung. "Simultaneous assessment of pre-and postsynaptic sites of the dopaminergic system: Dual isotope studies using [I-123] IBF/IBZM and [Tc-99m] TRODAT-1." In JOURNAL OF NUCLEAR MEDICINE, vol. 39, no. 5, pp. 7P-7P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1998.
12. Mozley, P. D., J. B. Stubbs, K. Plossl, S. Dresel, E. D. Barraclough, L. I. Araujo, A. Alavi, J. Saffer, and H. F. Kung. "The biodistribution and dosimetry of a technetium-99m labeled tropane for imaging dopamine transporters." In JOURNAL OF NUCLEAR MEDICINE, vol. 39, no. 5, pp. 221P-221P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1998.
13. Oya, S., M. P. Kung, M. Mu, and H. F. Kung. "New serotonin 5-HT1a receptor antagonists." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 216, pp. U243-U243. 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC, 1998.
14. Plossl, K., M. P. Kung, S. K. Meegalla, S. Dresel, S. A. Kushner, M. Mu, X. F. Huang, P. D. Mozley, and H. F. Kung. "[Tc-99m] M-TRODAT: An improved dopamine transporter imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 39, no. 5, pp. 6P-6P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1998.
15. Zhuang, Z. P., M. P. Kung, M. Mu, C. Hou, and H. F. Kung. "[Tc-99m] MIBG: Novel myocardial and neuroendocrine tumor imaging agents for sympathetic neurons." In JOURNAL OF NUCLEAR MEDICINE, vol. 39, no. 5, pp. 215P-215P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 1998.
1997
1. Allen AR, Singh A, Zhuang ZP, Kung MP, Kung HF, Lucki I. The 5-HT1A receptor antagonist p-MPPI blocks responses mediated by postsynaptic and presynaptic 5-HT1A receptors. Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):301-7. doi: 10.1016/s0091-3057(96)00339-5. PMID: 9164586.
2. Ichise M, Ballinger JR, Vines D, Tsai S, Kung HF. Simplified quantification and reproducibility studies of dopamine D2-receptor binding with iodine-123-IBF SPECT in healthy subjects. J Nucl Med. 1997 Jan;38(1):31-7. PMID: 8998145.
3. Kung MP, Stevenson DA, Plössl K, Meegalla SK, Beckwith A, Essman WD, Mu M, Lucki I, Kung HF. [99mTc]TRODAT-1: a novel technetium-99m complex as a dopamine transporter imaging agent. Eur J Nucl Med. 1997 Apr;24(4):372-80. doi: 10.1007/BF00881808. PMID: 9096087.
4. Kung MP, Stevenson DA, Zhuang ZP, Vessotskie JM, Chumpradit S, Sun XM, Kung HF. Characterization of a novel iodinated ligand, IPMPP, for human dopamine D4 receptors expressed in CHO cells. Life Sci. 1997;60(2):91-100. doi: 10.1016/s0024-3205(96)00598-x. PMID: 9000114.
5. Kung, M-P., K. Ploessl, S. K. Meegalla, and H. F. Kung. "A Kit Formulation for Preparation of [99mTc] TRODAT-I: A New Dopamine Transporter Imaging Agent." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS40 (1997): 263-268.
6. Laruelle M, Iyer RN, al-Tikriti MS, Zea-Ponce Y, Malison R, Zoghbi SS, Baldwin RM, Kung HF, Charney DS, Hoffer PB, Innis RB, Bradberry CW. Microdialysis and SPECT measurements of amphetamine-induced dopamine release in nonhuman primates. Synapse. 1997 Jan;25(1):1-14. doi: 10.1002/(SICI)1098-2396(199701)25:1<1::aid-syn1>3.0.CO;2-H. PMID: 8987142.
7. Meegalla SK, Plössl K, Kung MP, Chumpradit S, Stevenson DA, Kushner SA, McElgin WT, Mozley PD, Kung HF. Synthesis and characterization of technetium-99m-labeled tropanes as dopamine transporter-imaging agents. J Med Chem. 1997 Jan 3;40(1):9-17. doi: 10.1021/jm960532j. PMID: 9016323.
8. Shiue CY, Shiue GG, Mozley PD, Kung MP, Zhuang ZP, Kim HJ, Kung HF. P-[18F]-MPPF: a potential radioligand for PET studies of 5-HT1A receptors in humans. Synapse. 1997 Feb;25(2):147-54. doi: 10.1002/(SICI)1098-2396(199702)25:2<147::aid-syn5>3.0.CO;2-C. PMID: 9021895.
9. Staley JK, Talbot JZ, Ciliax BJ, Miller GW, Levey AI, Kung MP, Kung HF, Mash DC. Radioligand binding and immunoautoradiographic evidence for a lack of toxicity to dopaminergic nerve terminals in human cocaine overdose victims. Brain Res. 1997 Feb 7;747(2):219-29. doi: 10.1016/s0006-8993(96)01196-1. PMID: 9045996.
10. Tatsch K, Schwarz J, Mozley PD, Linke R, Pogarell O, Oertel WH, Fieber RS, Hahn K, Kung HF. Relationship between clinical features of Parkinson's disease and presynaptic dopamine transporter binding assessed with [123I]IPT and single-photon emission tomography. Eur J Nucl Med. 1997 Apr;24(4):415-21. doi: 10.1007/BF00881814. PMID: 9096093.
11. Vessotskie JM, Kung MP, Chumpradit S, Kung HF. Quantitative autoradiographic studies of dopamine D3 receptors in rat cerebellum using [125I]S(-)5-OH-PIPAT. Brain Res. 1997 Dec 5;778(1):89-98. doi: 10.1016/s0006-8993(97)01014-7. PMID: 9462880.
12. Vessotskie JM, Kung MP, Chumpradit S, Kung HF. Characterization of [125I]S(-)5-OH-PIPAT binding to dopamine D2-like receptors expressed in cell lines. Neuropharmacology. 1997 Jul;36(7):999-1007. doi: 10.1016/s0028-3908(97)00076-2. PMID: 9257944.
13. Chumpradit, S., M-P. Kung, M. Mu, C. Hou, and H. F. Kung. "Synthesis and Characterization of a [^ 9^ 9^ mTc] SCH23390 Derivative as a Selective Dopamine Di Receptor Imaging Agent." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 40 (1997): 437-438.
14. Kung, H. F., H. J. Kim, M. P. Kung, S. K. Meegalla, K. Plossl, and H. K. Lee. "Imaging of dopamine transporters in humans with technetium-99m TRODAT-1-Reply." EUROPEAN JOURNAL OF NUCLEAR MEDICINE 24, no. 4 (1997): 463-463.
15. Meegalla, S. K., K. Plössl, M-P. Kung, M. Mu, and H. F. Kung. "Structure-Activity Relationship of [^ 9^ 9^ mTc] TRODAT-1 Derivatives as New Dopamine Transporter Imaging Agents." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 40 (1997): 434-436.
16. Oya, S., M-P. Kung, M. Mu, and H. F. Kung. "Synthesis and Characterization of Tc-99m Labeled Imidazo [1, 5a][1, 4] Benzodiazepine Derivatives as Potential CNS Benzodiazepine Receptor Imaging Agents." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 40 (1997): 431-433.
17. Plössl, K., S. K. Meegalla, D. A. Stevenson, M. Mu, M-P. Kung, and H. F. Kung. "Specificity of Diastereomers of [ 99mTc] TRODAT-1 as Dopamine Transporter Imaging Agents." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 40 (1997): 428-430.
18. Schwarz, J., K. Tatsch, R. Linke, O. Pogarell, D. Mozley, and H. F. Kung. "Measuring the decline of dopamine transporter binding in patients with Parkinson's disease using 123I-IPT and SPECT." In Neurology, vol. 48, no. 3, pp. 25003-25003. 227 EAST WASHINGTON SQ, PHILADELPHIA, PA 19106: LIPPINCOTT-RAVEN PUBL, 1997.
19. Zhuang, Z-P., M-P. Kung, M. Mu, and H. F. Kung. "Cyclic Amide Derivatives of 4-(2'-Methoxy-) phenyl-1-[2'-(N-2"-Pyridinyl-)-(p-Iodobenzamido-]-ethylpiperazine (p-MPPI) as 5-HT~ 1~ A Receptor Ligands." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 40 (1997): 88-90.
20. Zhuang, Z-P., M-P. Kung, B. Liang, and H. F. Kung. "Synthesis and Characterization of Iodinated Adenosine Derivatives as Selective A~ 1 and A~ 2 Receptor Imaging Agents." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 40 (1997): 85-87.
1996
1. Ichise M, Ballinger JR, Golan H, Vines D, Luong A, Tsai S, Kung HF. Noninvasive quantification of dopamine D2 receptors with iodine-123-IBF SPECT. J Nucl Med. 1996 Mar;37(3):513-20. PMID: 8772658.
2. Kim HJ, Karp JS, Mozley PD, Yang SO, Moon DH, Kung HF, Lee HK, Alavi A. Stimulating technetium-99m cerebral perfusion studies with a three-dimensional Hoffmann brain phantom: collimator and filter selection in SPECT neuroimaging. Ann Nucl Med. 1996 Feb;10(1):153-60. doi: 10.1007/BF03165071. PMID: 8814722.
3. Kung, Hank F. "The development of radiopharmaceuticals for imaging CNS receptors." In Current Directions in Radiopharmaceutical Research and Development, pp. 99-113. Springer, Dordrecht, 1996.
4. Kung HF, Stevenson DA, Zhuang ZP, Kung MP, Frederick D, Hurt SD. New 5-HT1A receptor antagonist: [3H]p-MPPF. Synapse. 1996 Aug;23(4):344-6. doi: 10.1002/(SICI)1098-2396(199608)23:4<344::aid-syn13>3.0.CO;2-X. PMID: 8855520.
5. Kung HF, Kim HJ, Kung MP, Meegalla SK, Plössl K, Lee HK. Imaging of dopamine transporters in humans with technetium-99m TRODAT-1. Eur J Nucl Med. 1996 Nov;23(11):1527-30. doi: 10.1007/BF01254479. PMID: 8854853.
6. Kung HF, Frederick D, Kim HJ, McElgin W, Kung MP, Mu M, Mozley PD, Vessotskie JM, Stevenson DA, Kushner SA, Zhuang ZP. In vivo SPECT imaging of 5-HT1A receptors with [123I]p-MPPI in nonhuman primates. Synapse. 1996 Nov;24(3):273-81. doi: 10.1002/(SICI)1098-2396(199611)24:3<273::aid-syn10>3.0.CO;2-Y. PMID: 8923668.
7. Kung MP, Mu M, Zhuang ZP, Kung HF. NCS-MPP (4-(2'-methoxy-phenyl)-1-[2'-(N-2"-pyridyl)-p-isothiocyanobenz amido]-ethyl-piperazine): a high affinity and irreversible 5-HT1A receptor ligand. Life Sci. 1996;58(3):177-86. doi: 10.1016/0024-3205(95)02275-9. PMID: 9499158.
8. Kung, Mei-Ping, D. Andrew Stevenson, Zhi-Ping Zhuang, Janet M. Vessotskie, Sumalee Chumpradit, Xiao-Ming Sun, and Hank F. Kung. "Characterization of a novel iodinated ligand, IPMPP, for human dopamine D4 receptors expressed in CHO cells." Life sciences 60, no. 2 (1996): 91-100.
9. Mach RH, Nader MA, Ehrenkaufer RL, Line SW, Smith CR, Luedtke RR, Kung MP, Kung HF, Lyons D, Morton TE. Comparison of two fluorine-18 labeled benzamide derivatives that bind reversibly to dopamine D2 receptors: in vitro binding studies and positron emission tomography. Synapse. 1996 Dec;24(4):322-33. doi: 10.1002/(SICI)1098-2396(199612)24:4<322::aid-syn2>3.0.CO;2-F. PMID: 10638823.
10. Meegalla S, Plössl K, Kung MP, Chumpradit S, Stevenson DA, Frederick D, Kung HF. Tc-99m-labeled tropanes as dopamine transporter imaging agents. Bioconjug Chem. 1996 Jul-Aug;7(4):421-9. doi: 10.1021/bc960029l. PMID: 8853455.
11. Mozley PD, Stubbs JB, Kim HJ, McElgin W, Kung MP, Meegalla S, Kung HF. Dosimetry of an iodine-123-labeled tropane to image dopamine transporters. J Nucl Med. 1996 Jan;37(1):151-9. PMID: 8543985.
12. Mozley PD, Kim HJ, Gur RC, Tatsch K, Muenz LR, McElgin WT, Kung MP, Mu M, Myers AM, Kung HF. Iodine-123-IPT SPECT imaging of CNS dopamine transporters: nonlinear effects of normal aging on striatal uptake values. J Nucl Med. 1996 Dec;37(12):1965-70. PMID: 8970515.
13. Oya S, Kung MP, Frederick D, Kung HF. Novel TcVO(III) N2S2 complexes: interconversion by redox reaction. Nucl Med Biol. 1996 Jul;23(5):589-93. doi: 10.1016/0969-8051(96)00042-x. PMID: 8905823.
14. Pellevoisin C, Chalon S, Kung HF, Besnard JC, Guilloteau D. Is TISCH a suitable tracer for in vivo study of modifications of the dopamine D-1 receptor? Nucl Med Biol. 1996 Jan;23(1):75-8. doi: 10.1016/0969-8051(95)02070-5. PMID: 9004918.
15. Chumpradit, S., M. P. Kung, M. Mu, J. M. Vessotskie, and H. F. Kung. "Synthesis and binding studies of zaminoindansas selective ligands for dopamine D-2 receptors." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 212, pp. 150-MEDI. 1155 16TH ST, NW, WASHINGTON, DC 20036: AMER CHEMICAL SOC, 1996.
16. Ichise, Masanori, James R. Ballinger, Douglass Vines, Scott Tsai, and Hank F. Kung. "Simplified quantification and reproducibility studies of dopamine D2-receptor binding with iodine-123-IBF SPECT in healthy subjects." In JOURNAL OF NUCLEAR MEDICINE, vol. 37, no. 5, pp. 1254-1254. 1850 SAMUEL MORSE DR, RESTON, VA 22090-5316: SOC NUCLEAR MEDICINE INC, 1996.
17. Kushner, S. A., W. T. McElgin, P. D. Mozley, and H. F. Kung. "A fully-automated method of multi-modal coregistration using external fiducial markers." In JOURNAL OF NUCLEAR MEDICINE, vol. 37, no. 5, pp. 990-990. 1850 SAMUEL MORSE DR, RESTON, VA 22090-5316: SOC NUCLEAR MEDICINE INC, 1996.
18. Kushner, S. A., D. Frederick, M. P. Kung, P. D. Mozley, M. Mu, D. A. Stevenson, J. M. Vessotskie, and H. F. Kung. "Quantitative [I-123] IPT SPECT measurements: Comparisons with ex vivo dissection and in vitro binding assays in non-human primates." In JOURNAL OF NUCLEAR MEDICINE, vol. 37, no. 5, pp. 255-255. 1850 SAMUEL MORSE DR, RESTON, VA 22090-5316: SOC NUCLEAR MEDICINE INC, 1996.
19. Mozley, P. D., S. A. Kushner, D. Frederick, M. P. Kung, H. J. Kim, R. Malison, W. T. McElgin, J. Vessotskie, M. Mu, and H. F. Kung. "Dynamic SPECT measurements of the dopamine transporter: Reliability of [I-123] IPT uptake values in non-human primates." In JOURNAL OF NUCLEAR MEDICINE, vol. 37, no. 5, pp. 917-917. 1850 SAMUEL MORSE DR, RESTON, VA 22090-5316: SOC NUCLEAR MEDICINE INC, 1996.
20. Oya, S., M. P. Kung, D. A. Stevenson, and H. F. Kung. "Tc-99m labeled 5-HT1A receptor imaging agents." In JOURNAL OF NUCLEAR MEDICINE, vol. 37, no. 5, pp. 870-870. 1850 SAMUEL MORSE DR, RESTON, VA 22090-5316: SOC NUCLEAR MEDICINE INC, 1996.
21. Oya, S., and H. F. Kung. "In vivo and in vitro stability of small and neutral Tc-99m bisaminoethanethiol (BAT, N2S2) complexes." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 212, pp. 75-NUCL. 1155 16TH ST, NW, WASHINGTON, DC 20036: AMER CHEMICAL SOC, 1996.
22. Plossl, K., S. K. Meegalla, M. P. Kung, S. Chumpradit, D. A. Stevenson, D. Frederick, and H. F. Kung. "Tc-99m labeled tropanes as dopamine transporter imaging agents." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 212, pp. 84-MEDI. 1155 16TH ST, NW, WASHINGTON, DC 20036: AMER CHEMICAL SOC, 1996.
23. Schwarz, J., K. Tatsch, O. Pogarell, W. H. Oertel, P. D. Mozley, and H. F. Kung. "Imaging of dopamine nerve terminals in the striatum using the new cocaine analog I-123-IPT and SPECT in patients with Parkinson's disease and controls." In NEUROLOGY, vol. 46, no. 2, pp. 6092-6092. 34 BEACON STREET, BOSTON, MA 02108-1493: LITTLE BROWN CO, 1996.
1995
1. Baum S, Eckelman WC, Garcia EV, Holman BL, Kung HF, Mattrey RF, Piwnica-Worms D, Wahl RL, Watson JT. Contrast media and radiopharmaceutical agents: regulatory issues. Acad Radiol. 1995 Sep;2 Suppl 2:S92-3. doi: 10.1016/s1076-6332(12)80037-7. PMID: 9419707.
2. Burris KD, Pacheco MA, Filtz TM, Kung MP, Kung HF, Molinoff PB. Lack of discrimination by agonists for D2 and D3 dopamine receptors. Neuropsychopharmacology. 1995 Jul;12(4):335-45. doi: 10.1016/0893-133X(94)00099-L. PMID: 7576010.
3. Buck A, Westera G, Sutter M, Albani C, Kung HF, vonSchulthess GK. Iodine-123-IBF SPECT evaluation of extrapyramidal diseases. J Nucl Med. 1995 Jul;36(7):1196-200. PMID: 7790944.
4. Canney DJ, Kung MP, Kung HF. Amino- and amido-tetrabenazine derivatives: synthesis and evaluation as potential ligands for the vesicular monoamine transporter. Nucl Med Biol. 1995 May;22(4):527-35. doi: 10.1016/0969-8051(94)00118-4. PMID: 7550031.
5. Chumpradit, Sumalee, Mei‐Ping Kung, Janet Vessotskie, and Hank F. Kung. "Synthesis, resolution and radioiodination of S (−) trans‐5‐hydroxy‐2‐[N‐n‐propyl‐N‐(3′‐iodo‐2′‐propenyl) amino] tetralin‐S (−) trans‐5‐OH‐PIPAT: A new dopamine D2‐like receptor ligand." Journal of Labelled Compounds and Radiopharmaceuticals 36, no. 11 (1995): 1051-1062.
6. Kung HF. Single-photon tracers for single-photon emission computed tomography. Acad Radiol. 1995 Sep;2 Suppl 2:S94-5. doi: 10.1016/s1076-6332(12)80038-9. PMID: 9419708.
7. Kung MP, Essman WD, Frederick D, Meegalla S, Goodman M, Mu M, Lucki I, Kung HF. IPT: a novel iodinated ligand for the CNS dopamine transporter. Synapse. 1995 Aug;20(4):316-24. doi: 10.1002/syn.890200405. PMID: 7482291.
8. Kung, Mei-Ping, Mu Mu, Zhi-Ping Zhuang, and Hank F. Kung. "NCS-MPP (4-(2′-METHOXY-PHENYL)-1-[2′-(N-2 ″-PYRIDYL)-P-Isothiocyanobenzamido]-Ethyl-Piperazine): A high affinity and irreversible 5-HT1A receptor ligand." Life sciences 58, no. 3 (1995): 177-186.
9. Kung MP, Frederick D, Mu M, Zhuang ZP, Kung HF. 4-(2'-Methoxy-phenyl)-1-[2'-(n-2"-pyridinyl)-p-iodobenzamido]-ethyl- piperazine ([125I]p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain: in vitro binding and autoradiographic studies. J Pharmacol Exp Ther. 1995 Jan;272(1):429-37. PMID: 7815360.
10. Laruelle M, Abi-Dargham A, van Dyck CH, Rosenblatt W, Zea-Ponce Y, Zoghbi SS, Baldwin RM, Charney DS, Hoffer PB, Kung HF, et al. SPECT imaging of striatal dopamine release after amphetamine challenge. J Nucl Med. 1995 Jul;36(7):1182-90. PMID: 7790942.
11. Malison RT, Vessotskie JM, Kung MP, McElgin W, Romaniello G, Kim HJ, Goodman MM, Kung HF. Striatal dopamine transporter imaging in nonhuman primates with iodine-123-IPT SPECT. J Nucl Med. 1995 Dec;36(12):2290-7. PMID: 8523122.
12. Meegalla, Sanath, Karl Ploessl, Mei-Ping Kung, D. Andrew Stevenson, Louise M. Liable-Sands, Arnold L. Rheingold, and Hank F. Kung. "First example of a 99mTc complex as a dopamine transporter imaging agent." Journal of the American Chemical Society 117, no. 44 (1995): 11037-11038.
13. Mozley PD, Stubbs JB, Kim HJ, McElgin W, Chumpradit S, Kung MP, Romaniello G, Kung HF. Dosimetry of a D2/D3 dopamine receptor antagonist that can be used with PET or SPECT. J Nucl Med. 1995 Jul;36(7):1322-31. PMID: 7790963.
14. Oya S, Kung MP, Frederick D, Kung HF. New bisaminoethanethiol (BAT) ligands which form two interconvertible Tc-99m complexes. Nucl Med Biol. 1995 Aug;22(6):749-57. doi: 10.1016/0969-8051(95)00021-o. PMID: 8535335.
15. Staley, J. K., C. V. Wetli, A. J. Ruttenber, W. Lee Hearn, H. F. Kung, and D. C. Mash. "Dopamine transporter and receptor autoradiography in cocaine psychosis and sudden death." Biological Psychiatry 9, no. 37 (1995): 656-657.
16. Vessotskie JM, Kung MP, Chumpradit S, Romaniello G, McElgin W, Frederick D, Malison RT, Kung HF. In vitro and in vivo characterization of R(+)-FIDA2: a dopamine D2-like imaging agent. J Nucl Med. 1995 Jul;36(7):1282-8. PMID: 7790957.
17. Zhuang ZP, Kung MP, Clarke W, Maayani S, Mu M, Kung HF. Synthesis of (+)-(R)- and (-)-(S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)] aminotetralin: new 5-HT1A receptor ligands. Chirality. 1995;7(6):452-8. doi: 10.1002/chir.530070611. PMID: 7577352.
18. Chumpradit, S., J. Vessotskie, M-P. Kung, and H. F. Kung. "Synthesis and Binding Studies of 2-Aminotetralins and 3-Aminobenzopyrans as Selective Ligands for Dopamine D2 Receptors at High Affinity States." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 37 (1995): 31-33.
19. Joyce, J. N., E. V. Gurevich, H. F. Kung, M-P. Kung, Y. Bordelon, R. Shapiro, S. E. Arnold, and R. E. Gur. "Dopamine D3 receptors are elevated in schizophrenic brain and decreased by neuroleptic treatment." Schizophrenia Research1, no. 15 (1995): 61.
20. KUNG, MEl-PING, DANA FREDERICK, MU MU, ZHI-PING ZHUANG, and HANK F. KUNG. "Ethyl-Piperazine ([l2bI] pMPPI) as a New Selective Radioligand of Serotonin-1A Sites in Rat Brain: In Vitro Binding and Autoradiographic Studies1." (1995).
21. Mach, R. H., R. L. E. Ehrenkaufer, M. A. Nader, S. W. Line, C. R. Smith, C. Hubbard, M-P. Kung, H. F. Kung, R. R. Luedtke, and T. E. Morton. "Validation Studies of [^ 1^ 8F] Fluoroclebopride ([^ 1^ 8F] FCP): A Benzamide Analogue that Binds Reversibly to Dopamine D~ 2 Receptors." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 37 (1995): 21-23.
22. MASH, DC, JK STALEY, MP KUNG, HF KUNG, and WJ WEINER. "VISUALIZING THE HUMAN VESICULAR MONOAMINE TRANSPORTER IN-VITRO WITH I-125 IODOVINYLTETRA-BENAZINE." In NEUROLOGY, vol. 45, no. 4, pp. A409-A410. 34 BEACON STREET, BOSTON, MA 02108-1493: LITTLE BROWN CO, 1995.
23. Meegalla, S. K., Z-P. Zhuang, S. Chumpradit, H-E. Wang, M-P. Kung, J. Vessotskie, D. A. Stevenson, and H. F. Kung. "Synthesis and Binding Studies of N-([2'-Pyrrodidinyl] Methyl)-2, 3-Dimethoxy-5-Iodobenzamides as PET and SPECT Imaging Agents for Dopamine D2 and D3 Receptors." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 37 (1995): 34-36.
24. Oya, S., M-P. Kung, D. Frederick, and H. F. Kung. "Novel Tc^ VO (III) N~ 2S~ 2 Complexes: Interconversion by Redox Reaction." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 37 (1995): 779-781.
25. Oya, S., K. Plössl, M-P. Kung, D. A. Stevenson, and H. F. Kung. "Small and Neutral Tc^ VO (III) N~ 2S~ 2 Complexes for Developing New Brain Imaging Agents." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS37 (1995): 782-784.
26. Plössl, K., Z-P. Zhuang, S. K. Meegalla, J. Bradshaw, D. Frederick, D. A. Stevenson, M-P. Kung, and H. F. Kung. "Tc-99m [MPP] Complexes: Potential 5-HT~ 1~ A Receptor Imaging Agents." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 37 (1995): 306-308.
27. Yeping, Xu, Liu Boli, and H. F. Kung. "Study on QSAR of brain radiopharmaceuticals of iodoamphetamines." Journal of Nuclear and Radiochemistry (He Huaxue Yu Fangshe Huaxue) 17 (1995).
28. ZHUANG, ZHI-PING, MEI-PING KUNG, WILLIAM CLARKE, SAUL MAAYANI, MU MU, and HANK F. KUNG. "Aminotetralin: New 5-HTlA Receptor Ligands." CHIRALITY 7, no. 45 (1995): 458.
29. Zhuang, Z-P., S. D. Hurt, D. A. Stevenson, M-P. Kung, and H. F. Kung. "Synthesis and Binding Studies of [^ 3H] MPPI and [^ 3H] MPPF: Radioactive Antagonist Ligands for 5-HT~ 1~ A Receptors." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 37 (1995): 297-298.
