HANK & LIN'S GROUP
The past is prologue and the future is scintillating
2004
1. Choi, Hoon, Seok Rye Choi, Rong Zhou, Hank F. Kung, and I-Wei Chen. "Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery1." Academic radiology 11, no. 9 (2004): 996-1004.
2. Kung HF, Newman S, Choi SR, Oya S, Hou C, Zhuang ZP, Acton PD, Plössl K, Winkler J, Kung MP. 2-(2-(dimethylaminomethyl)phenoxy)-5-iodophenylamine: an improved serotonin transporter imaging agent. J Med Chem. 2004 Oct 7;47(21):5258-64. doi: 10.1021/jm049917p. PMID: 15456270.
3. Kung, H. F. "Imaging of Aβ plaques in the brain of Alzheimer's disease." In International Congress Series, vol. 1264, pp. 3-9. Elsevier, 2004.
4. Kung MP, Zhuang ZP, Hou C, Kung HF. Development and evaluation of iodinated tracers targeting amyloid plaques for SPECT imaging. J Mol Neurosci. 2004;24(1):49-53. doi: 10.1385/JMN:24:1:049. PMID: 15314249.
5. Kung MP, Hou C, Zhuang ZP, Cross AJ, Maier DL, Kung HF. Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice. Eur J Nucl Med Mol Imaging. 2004 Aug;31(8):1136-45. doi: 10.1007/s00259-004-1487-z. Epub 2004 Mar 9. PMID: 15007564.
6. Kung MP, Choi SR, Hou C, Zhuang ZP, Foulon C, Kung HF. Selective binding of 2-[125I]iodo-nisoxetine to norepinephrine transporters in the brain. Nucl Med Biol. 2004 Jul;31(5):533-41. doi: 10.1016/j.nucmedbio.2004.03.001. PMID: 15219270.
7. Kung MP, Hou C, Zhuang ZP, Skovronsky D, Kung HF. Binding of two potential imaging agents targeting amyloid plaques in postmortem brain tissues of patients with Alzheimer's disease. Brain Res. 2004 Oct 29;1025(1-2):98-105. doi: 10.1016/j.brainres.2004.08.004. Erratum in: Brain Res. 2005 Jan 21;1031(2):302. PMID: 15464749.
8. McKinnon, S. J., L. T. Kasmala, and H. F. Kung. "Fluorescent Imaging of Amyloid in Eyes and Brains of Chronic Ocular Hypertension (COH) Rats After Intravenous Injection of Soluble K–114 Dye." Investigative Ophthalmology & Visual Science 45, no. 13 (2004): 2294-2294.
9. Newberg AB, Plössl K, Mozley PD, Stubbs JB, Wintering N, Udeshi M, Alavi A, Kauppinen T, Kung HF. Biodistribution and imaging with (123)I-ADAM: a serotonin transporter imaging agent. J Nucl Med. 2004 May;45(5):834-41. PMID: 15136634.
10. Stoll, Timo, Johannes Ermert, Shunichi Oya, Hank F. Kung, and Heinz H. Coenen. "Application of nca 4‐[18F] fluorophenol in diaryl ether syntheses of 2‐(4‐[18F] fluorophenoxy)‐benzylamines." Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal of the International Isotope Society 47, no. 7 (2004): 443-455.
11. Verhoeff NP, Wilson AA, Takeshita S, Trop L, Hussey D, Singh K, Kung HF, Kung MP, Houle S. In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PET. Am J Geriatr Psychiatry. 2004 Nov-Dec;12(6):584-95. doi: 10.1176/appi.ajgp.12.6.584. PMID: 15545326.
12. Verhoeff, N. P. L. G., A. A. Wilson, H. F. Kung, D. Hussey, L. Trop, and S. Houle. "β-Amyloid imaging in vivo and its possible implications for Alzheimer’s disease." In Nuclear Medicine in Psychiatry, pp. 191-199. Springer, Berlin, Heidelberg, 2004.
13. Wilson, Alan A., Armando Garcia, Alexandra Chestakova, Hank Kung, and Sylvain Houle. "A rapid one‐step radiosynthesis of the β‐amyloid imaging radiotracer N‐methyl‐[11C] 2‐(4′‐methylaminophenyl)‐6‐hydroxybenzothiazole ([11C]‐6‐OH‐BTA‐1)." Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal of the International Isotope Society 47, no. 10 (2004): 679-682.
14. Hou, Catherine, Mei-Ping Kung, Yan Xiu, Daniel M. Skovronsky, Robert Mach, and Hank F. Kung. "P2-188 Labeling amyloid plaque-like structures by radioiodinated ligands in rhesus monkey brain." Neurobiology of Aging 25 (2004): S281.
15. Kung, Hank F., Mei-Ping Kung, Zhi-Ping Zhuang, Chi-Wan Lee, and Catherine Hou. "P2-151 Biphenyl derivatives as specific binding agents for Aβ aggregates." Neurobiology of Aging 25 (2004): S268.
16. Kung, Mei-Ping, Catherine Hou, Zhi-Ping Zhuang, Daniel M. Skovronsky, and Hank F. Kung. "O3-03-02 Binding of two potential imaging agents targeting amyloid plaques in Alzheimer's disease brains." Neurobiology of Aging 25 (2004): S57.
17. Skovronsky, Daniel, Alexander R. Judkins, Mei-Ping Kung, Mark Forman, Daniel Martinez, Catherine Hou, Zhi-Ping Zhuang, and Hank F. Kung. "P3-079 Characterization of neurodegenerative disease radioligands by tissue microarray analysis." Neurobiology of Aging 25 (2004): S375-S376.
18. Verhoeff, Nicolaas P., Alan A. Wilson, Jose Nobrega, David Westaway, Peter St George-Hyslop, Doug Hussey, Shinichiro Takeshita et al. "O3-03-07 [11C] SB-13 PET: a valid alternative for β-amyloid imaging in vivo?." Neurobiology of Aging 25 (2004): S58-S59.
19. Zhou, R., H. Choi, I. Corbin, S. Choi, H. Li, B. Gray, J. D. Glickson, I. W. Chen, and H. Kung. "MR imaging of low density lipoprotein and folate receptors." ISMRM Kyoto (2004): 286.
2003
1. Acton PD, Kung HF. Small animal imaging with high resolution single photon emission tomography. Nucl Med Biol. 2003 Nov;30(8):889-95. doi: 10.1016/s0969-8051(03)00112-4. PMID: 14698793.
2. Auricchio A, Acton PD, Hildinger M, Louboutin JP, Plössl K, O'Connor E, Kung HF, Wilson JM. In vivo quantitative noninvasive imaging of gene transfer by single-photon emission computerized tomography. Hum Gene Ther. 2003 Feb 10;14(3):255-61. doi: 10.1089/10430340360535805. PMID: 12639305.
3. Kung HF, Kung MP, Choi SR. Radiopharmaceuticals for single-photon emission computed tomography brain imaging. Semin Nucl Med. 2003 Jan;33(1):2-13. doi: 10.1053/snuc.2003.127296. PMID: 12605353.
4. Kung HF, Kung MP, Zhuang ZP, Hou C, Lee CW, Plössl K, Zhuang B, Skovronsky DM, Lee VM, Trojanowski JQ. Iodinated tracers for imaging amyloid plaques in the brain. Mol Imaging Biol. 2003 Nov-Dec;5(6):418-26. doi: 10.1016/j.mibio.2003.09.003. PMID: 14667496.
5. Kung, H F. "Receptor Specific Ligands for Spect Imaging". 2003.United States. https://doi.org/10.2172/836898. https://www.osti.gov/servlets/purl/836898.
6. Kung MP, Skovronsky DM, Hou C, Zhuang ZP, Gur TL, Zhang B, Trojanowski JQ, Lee VM, Kung HF. Detection of amyloid plaques by radioligands for Abeta40 and Abeta42: potential imaging agents in Alzheimer's patients. J Mol Neurosci. 2003 Feb;20(1):15-24. doi: 10.1385/JMN:20:1:15. PMID: 12663930.
7. Kung MP, Zhuang ZP, Hou C, Jin LW, Kung HF. Characterization of radioiodinated ligand binding to amyloid beta plaques. J Mol Neurosci. 2003;20(3):249-54. doi: 10.1385/JMN:20:3:249. PMID: 14501004.
8. Lee CW, Kung MP, Hou C, Kung HF. Dimethylamino-fluorenes: ligands for detecting beta-amyloid plaques in the brain. Nucl Med Biol. 2003 Aug;30(6):573-80. doi: 10.1016/s0969-8051(03)00050-7. PMID: 12900283.
9. Ono M, Wilson A, Nobrega J, Westaway D, Verhoeff P, Zhuang ZP, Kung MP, Kung HF. 11C-labeled stilbene derivatives as Abeta-aggregate-specific PET imaging agents for Alzheimer's disease. Nucl Med Biol. 2003 Aug;30(6):565-71. doi: 10.1016/s0969-8051(03)00049-0. PMID: 12900282.
10. Shiue GG, Choi SR, Fang P, Hou C, Acton PD, Cardi C, Saffer JR, Greenberg JH, Karp JS, Kung HF, Shiue CY. N,N-dimethyl-2-(2-amino-4-(18)F-fluorophenylthio)-benzylamine (4-(18)F-ADAM): an improved PET radioligand for serotonin transporters. J Nucl Med. 2003 Dec;44(12):1890-7. PMID: 14660713.
11. Zhuang ZP, Kung MP, Wilson A, Lee CW, Plössl K, Hou C, Holtzman DM, Kung HF. Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain. J Med Chem. 2003 Jan 16;46(2):237-43. doi: 10.1021/jm020351j. PMID: 12519062.
12. Zhuang, Zhi‐Ping, Mei‐Ping Kung, Masahiro Ono, Catherine Hou, and Hank F. Kung. "Syntheses of Two Potential Ligands for Tc‐99m Labeling as Diagnosis Agents of Alzheimer's Disease." Chinese Journal of Chemistry 21, no. 7 (2003): 824-832.
13. Acton, P. D., K. Plossl, C. Hou, M. P. Kung, and H. F. Kung. "Simultaneous dual isotope SPECT imaging of pre-and post-synaptic dopamine binding sites in a hemi-lesioned mouse model of Parkinson's disease." In JOURNAL OF NUCLEAR MEDICINE, vol. 44, no. 5, pp. 115P-116P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2003.
14. Kung, H. F., Z. P. Zhuang, M. P. Kung, and C. Hou. "Tc-99m Labeled Biphenyls as Ass Plaque-Specific Imaging Agents." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 46 (2003): S150-S150.
15. Newberg, A., G. Baltuch, P. D. Mozley, H. Kung, H. Hurtig, K. Ploessl, N. Wintering, M. Udeshi, and P. Acton. "Longitudinal evaluation of dopamine transporters in Parkinson's patients treated with subthalamic nuclei stimulation surgery compared to medication." In JOURNAL OF NUCLEAR MEDICINE, vol. 44, no. 5, pp. 119P-119P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2003.
16. Oya, S., S. R. Choi, and H. F. Kung. "Synthesis and characterization of a Tc-99m labeled biphenylthiol as serotonin transporter imaging agent." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 226, pp. U33-U34. 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC, 2003.
17. Oya, S., S-R. Choi, C. Hou, K. Plossl, P. D. Acton, and H. F. Kung. "^ 1^ 8F (2-[(2-Amino-5-Fluorophenyl) Thio]-N, N-Dimethyl-Benzenmethanamine) as a PET Imaging Agent for Serotonin Transporters." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 46 (2003): S164-S164.
18. Plossl, K., S. R. Choi, S. Oya, A. Newberg, and H. F. Kung. "Improved preparation of [I-123] ADAM, for human studies." In JOURNAL OF NUCLEAR MEDICINE, vol. 44, no. 5, pp. 100P-100P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2003.
19. Udeshi, M., A. Newberg, H. Hurtig, A. Siderowf, P. D. Mozley, M. Stern, K. Plossl et al. "Dopamine transporter uptake differentiates patients with progressive supranuclear palsy." In JOURNAL OF NUCLEAR MEDICINE, vol. 44, no. 5, pp. 235P-235P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2003.
20. Udeshi, M., Newberg, A., Hurtig, H., Mozley, P.D., Wintering, N., Stern, M., Siderowf, A., Plossl, K., Mozley, L., Alavi, A. and Acton, P., 2003, May. Evaluation of Dopamine transporter uptake in patients with multiple system atrophy. In Journal of Nuclear Medicine (Vol. 44, No. 5, pp. 236P-236P). 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC.
21. Wilson, A. A., J. Nobrega, S. Houle, D. Westaway, P. Verhoeff, Z-P. Zhuang, M-P. Kung, and H. Kung. "Radiosynthesis and Evaluation of Potential beta-Amyloid Imaging Radiotracers for PET." JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS 46 (2003): S61-S61.
22. Wintering, N., A. Newberg, M. Udeshi, H. Hurtig, K. Plossl, A. Siderowf, M. Stern et al. "Differentiating hemi-Parkinson's from Parkinson's using TRODAT SPECT imaging." In Journal of Nuclear Medicine, vol. 44, no. 5, pp. 236P-236P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2003.
2002
1. Acton PD, Choi SR, Plössl K, Kung HF. Quantification of dopamine transporters in the mouse brain using ultra-high resolution single-photon emission tomography. Eur J Nucl Med Mol Imaging. 2002 May;29(5):691-8. doi: 10.1007/s00259-002-0776-7. Epub 2002 Mar 7. PMID: 11976810.
2. Acton PD, Hou C, Kung MP, Plössl K, Keeney CL, Kung HF. Occupancy of dopamine D2 receptors in the mouse brain measured using ultra-high-resolution single-photon emission tomography and [123]IBF. Eur J Nucl Med Mol Imaging. 2002 Nov;29(11):1507-15. doi: 10.1007/s00259-002-0903-5. PMID: 12537007.
3. Acton PD, Kung MP, Hou C, Plössl K, Keeney C, Kung HF. Ultra-high resolution single photon emission tomography imaging of the mouse striatum. Eur J Nucl Med Mol Imaging. 2002 Mar;29(3):446. doi: 10.1007/s00259-002-0770-0. PMID: 12002724.
4. Huang Y, Hwang DR, Narendran R, Sudo Y, Chatterjee R, Bae SA, Mawlawi O, Kegeles LS, Wilson AA, Kung HF, Laruelle M. Comparative evaluation in nonhuman primates of five PET radiotracers for imaging the serotonin transporters: [11C]McN 5652, [11C]ADAM, [11C]DASB, [11C]DAPA, and [11C]AFM. J Cereb Blood Flow Metab. 2002 Nov;22(11):1377-98. doi: 10.1097/01.WCB.0000040948.67415.05. PMID: 12439295.
5. Kung, Hank F., and Mei‐Ping Kung. "Imaging Monoamine Transporters in the Brain." Transmembrane Transporters(2002): 239-257.
6. Kung MP, Hou C, Zhuang ZP, Zhang B, Skovronsky D, Trojanowski JQ, Lee VM, Kung HF. IMPY: an improved thioflavin-T derivative for in vivo labeling of beta-amyloid plaques. Brain Res. 2002 Nov 29;956(2):202-10. doi: 10.1016/s0006-8993(02)03436-4. PMID: 12445687.
7. Kung MP, Hou C, Zhuang ZP, Skovronsky DM, Zhang B, Gur TL, Trojanowski JQ, Lee VM, Kung HF. Radioiodinated styrylbenzene derivatives as potential SPECT imaging agents for amyloid plaque detection in Alzheimer's disease. J Mol Neurosci. 2002 Aug-Oct;19(1-2):7-10. doi: 10.1007/s12031-002-0003-9. PMID: 12212796.
8. Kung, Mei-Ping, Zhi-Ping Zhuang, Catherine Hou, Daniel Skovronsky, Tamar Gur, Sumalee Chumpradit, and Hank F. Kung. "Novel p-Amyloid Probes." Drug discovery and development for Alzheimer's disease 2000 (2002): 50.
9. Krause, Klaus-Henning, Stefan Dresel, Johanna Krause, Hank F. Kung, and Hanns Lochmüller. "Elevated striatal dopamine transporter in a drug naive patient with Tourette syndrome and attention deficit/hyperactivity disorder: positive effect of methylphenidate." Journal of neurology 249, no. 8 (2002): 1116-1118.
10. Krause, Klaus-Henning, Stefan H. Dresel, Johanna Krause, Hank F. Kung, Klaus Tatsch, and Manfred Ackenheil. "Stimulant-like action of nicotine on striatal dopamine transporter in the brain of adults with attention deficit hyperactivity disorder." International Journal of Neuropsychopharmacology 5, no. 2 (2002): 111-113.
11. Ono M, Kung MP, Hou C, Kung HF. Benzofuran derivatives as Abeta-aggregate-specific imaging agents for Alzheimer's disease. Nucl Med Biol. 2002 Aug;29(6):633-42. doi: 10.1016/s0969-8051(02)00326-8. PMID: 12234587.
12. Oya S, Choi SR, Coenen H, Kung HF. New PET imaging agent for the serotonin transporter: [(18)F]ACF (2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine). J Med Chem. 2002 Oct 10;45(21):4716-23. doi: 10.1021/jm020167y. PMID: 12361398.
13. Acton, P., M. P. Kung, C. Hou, K. Plossl, C. Keeney, and H. Kung. "Occupancy of dopamine D2 receptors in the mouse brain measured using ultra-high resolution single photon emission tomography." In NEUROIMAGE, vol. 16, no. 3, pp. S44-S44. 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2002.
14. Acton, P. D., A. Auricchio, K. Plossl, M. Hildinger, J. M. Wilson, and H. F. Kung. "In vivo non-invasive imaging of gene transfer with single photon emission tomography." In JOURNAL OF NUCLEAR MEDICINE, vol. 43, no. 5, pp. 120P-121P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2002.
15. Acton, P., S. R. Choi, K. Plossl, and H. Kung. "Ultra-high resolution single photon emission tomography imaging of dopamine transporters in the mouse brain." In NEUROIMAGE, vol. 16, no. 3, pp. S36-S36. 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2002.
16. Acton, Paul, Mei-Ping Kung, Catherine Hou, Karl Plössl, Cindy Keeney, and Hank Kung. "Ultra-high resolution single photon emission tomography imaging of the mouse striatum." European journal of nuclear medicine and molecular imaging29, no. 3 (2002): 446.
17. Castanon, Nathalie, M. Zhou, A. Lira, M. Bradley-Moore, J. Lira, H. F. Kung, M. A. Hofer, René Hen, and J. A. Gingrich. "Increased depression-related behaviors in serotonin transporter deficient mice." In Annual Meeting of the American Society for Neuroscience. 2002.
18. Kim, D. H., A. Kozlov, H. Kung, M. C. Kung, and P. J. Andersen. "Effect of preparation and redox treatment on the properties of ceria-zirconia oxide supported on alumina." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 223, pp. C12-C12. 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC, 2002.
19. Krause, J., S. H. Dresel, K. H. Krause, H. F. Kung, and K. Tatsch. "Direct action of nicotine on the striatal dopamine transporter? Results of a SPECT study with [Tc-99m] TRODAT-1 in adults with ADHD." In EUROPEAN NEUROPSYCHOPHARMACOLOGY, vol. 12, pp. S17-S18. PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE BV, 2002.
20. Kung, H. "Novel stilbenes as Abeta-plaque imaging agents." In JOURNAL OF NUCLEAR MEDICINE, vol. 43, no. 5, pp. 359P-359P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2002.
21. Kung, H. "Synthesis and characterization of I-125/I-123 IMPY as an Abeta-plaque imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 43, no. 5, pp. 166P-166P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2002.
22. Kung, H., K. Plossl, S. R. Choi, and S. Meegalla. "A new kit formulation for preparation of Tc-99m TRODAT-1." In JOURNAL OF NUCLEAR MEDICINE, vol. 43, no. 5, pp. 381P-381P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2002.
23. Kung, H. "Benzofuran derivatives as Abeta-plaque imaging agents." In JOURNAL OF NUCLEAR MEDICINE, vol. 43, no. 5, pp. 361P-361P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2002.
24. Kung, Mei-Ping, Chi-Wan Lee, Zhi-Ping Zhuang, Masahiro Ono, Catherine Hou, Karl Ploessl, and Hank Kung. "Novel Tracers for Imaging Amyloid Plaques." In Neuroimage, vol. 16, no. 3, pp. S1-S1. 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2002.
25. Lynch, D. R., S. Sokol, N. F. Maas, L. J. Balcer, A. D. Siderowf, H. F. Kung, and P. D. Mozley. "Influence of genetic polymorphisms on the specific uptake values of Tc-99m TRODAT-1 in patients with Parkinson's disease and healthy human research volunteers." In JOURNAL OF NUCLEAR MEDICINE, vol. 43, no. 5, pp. 19P-19P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2002.
26. Oya, S., S. R. Choi, H. Coenan, and H. Kung. "A fluorinated ADAM derivative as a serotonin transporter imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 43, no. 5, pp. 165P-165P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2002.
27. Stoll, T, Ermert, J, Coenen, H H, Choi, S R, and Kung, H F. 2002. "Syntheses of new 4-[18F] fluorophenoxy-containing radioligands for serotonin reuptake or transporter sites." Germany.
2001
1. Acton PD, Choi SR, Hou C, Plössl K, Kung HF. Quantification of serotonin transporters in nonhuman primates using [(123)I]ADAM and SPECT. J Nucl Med. 2001 Oct;42(10):1556-62. PMID: 11585873.
2. Ametamey, S., W. C. Eckelman, S. Oya, S. R. Choi, C. Hou, M. P. Kung, P. D. Acton, C. Y. Shiue, and H. F. Kung. "Session 2 Positron Emitters II: Transporters, Receptors-MONDAY AM-A6-SYNTHESIS AND CHARACTERIZATION OF 18F-IDAM AS A PET IMAGING AGENT FOR SEROTONIN TRANSPORTERS." Journal of Labelled Compounds and Radiopharmaceuticals 44, no. 1 (2001): 15-17.
3. Choi SR, Yang B, Plössl K, Chumpradit S, Wey SP, Acton PD, Wheeler K, Mach RH, Kung HF. Development of a Tc-99m labeled sigma-2 receptor-specific ligand as a potential breast tumor imaging agent. Nucl Med Biol. 2001 Aug;28(6):657-66. doi: 10.1016/s0969-8051(01)00234-7. PMID: 11518647.
4. Choi, S. R., S. Oya, C. Hou, and H. F. Kung. "Poster Session G-Positron Emitters and Halogens: Radiopharmaceuticals-G9-STRUCTURE-ACTIVITY RELATIONSHIP OF ANALOGS OF ADAM AS LIGANDS FOR SEROTONIN TRANSPORTERS." Journal of Labelled Compounds and Radiopharmaceuticals44, no. 1 (2001): 190-192.
5. Chumpradit, S., S. R. Choi, Z. P. Zhuang, and H. F. Kung. "Poster Session G-Positron Emitters and Halogens: Radiopharmaceuticals-G21-A NOVEL IODINATED BEZAMIDE DERIVATIVE FOR IMAGING ENDOGENOUS DOPAMINE." Journal of Labelled Compounds and Radiopharmaceuticals44, no. 1 (2001): 225-227.
6. Lee CW, Zhuang ZP, Kung MP, Plössl K, Skovronsky D, Gur T, Hou C, Trojanowski JQ, Lee VM, Kung HF. Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain. J Med Chem. 2001 Jul 5;44(14):2270-5. doi: 10.1021/jm010161t. PMID: 11428920.
7. Kung HF. Development of Tc-99m labeled tropanes: TRODAT-1, as a dopamine transporter imaging agent. Nucl Med Biol. 2001 Jul;28(5):505-8. doi: 10.1016/s0969-8051(01)00220-7. PMID: 11516695.
8. Kung HF, Lee CW, Zhuang ZP, Kung MP, Hou C, Plössl K. Novel stilbenes as probes for amyloid plaques. J Am Chem Soc. 2001 Dec 19;123(50):12740-1. doi: 10.1021/ja0167147. PMID: 11741464.
9. Mach, Robert H., Kenneth T. Wheeler, Suwanna Blair, Biao Yang, Cynthia S. Day, Joseph B. Blair, Seok‐Rye Choi, and Hank F. Kung. "Preparation of a technetium‐99m SPECT agent for imaging the sigma‐2 receptor status of solid tumors." Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal of the International Isotope Society 44, no. 13 (2001): 899-908.
10. MacDonald, Lawrence R., Bradley E. Patt, Jan S. Iwanczyk, Benjamin MW Tsui, Yuchuan Wang, Eric C. Frey, Daniel E. Wessell, Paul D. Acton, and Hank F. Kung. "Pinhole SPECT of mice using the LumaGEM gamma camera." IEEE Transactions on Nuclear Science 48, no. 3 (2001): 830-836.
11. Schmidt, Marie L., Theresa Schuck, Shelly Sheridan, Mei-Ping Kung, Hank Kung, Zhi-Ping Zhuang, Catherine Bergeron et al. "The fluorescent Congo red derivative,(trans, trans)− 1-bromo-2, 5-Bis-(3-hydroxycarbonyl-4-hydroxy) styrylbenzene (BSB), labels diverse β-pleated sheet structures in postmortem human neurodegenerative disease brains." The American journal of pathology 159, no. 3 (2001): 937-943.
12. Westera, G., J. S. Fowler, Z. P. Zhuang, M. P. Kung, C. Hou, C. W. Lee, J. Q. Trojanowski, V. MY Lee, and H. F. Kung. "Session 3 Positron Emitters and Halogens: Brain Tracers-MONDAY PM-A11-NOVEL PROBES FOR IMAGING AMYLOID: IODINATED BENZOTHIAZOLE DERIVATIVES." Journal of Labelled Compounds and Radiopharmaceuticals44, no. 1 (2001): 29-32.
13. Zhuang ZP, Kung MP, Hou C, Skovronsky DM, Gur TL, Plössl K, Trojanowski JQ, Lee VM, Kung HF. Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. J Med Chem. 2001 Jun 7;44(12):1905-14. doi: 10.1021/jm010045q. PMID: 11384236.
14. Zhuang, Zhi-Ping, Mei-Ping Kung, Catherine Hou, Karl Plössl, Daniel Skovronsky, Tamar L. Gur, John Q. Trojanowski, Virginia M-Y. Lee, and Hank F. Kung. "IBOX (2-(4′-dimethylaminophenyl)-6-iodobenzoxazole): a ligand for imaging amyloid plaques in the brain." Nuclear medicine and biology 28, no. 8 (2001): 887-894.
15. Zhuang, Z‐P., M‐P. Kung, C. Hou, C‐W. Lee, J. Q. Trojanowski, VM‐Y. Lee, and H. F. Kung. "Novel probes for imaging amyloid: Iodinated benzothiazole derivatives." Journal of Labelled Compounds and Radiopharmaceuticals 44, no. S1 (2001): S29-S32.
16. Zhuang, Z‐P., M‐P. Kung, C. Hou, C‐W. Lee, J. Q. Trojanowski, VM‐Y. Lee, and H. F. Kung. "Radioiodinated styrylbenzene derivatives as probes for imaging amyloid." Journal of Labelled Compounds and Radiopharmaceuticals44, no. S1 (2001): S236-S238.
17. Acton, P. D., A. Auricchio, K. Plossl, M. Hildinger, J. M. Wilson, and H. F. Kung. "Imaging gene expression with (99m) TcTRODAT-1 and single photon emission tomography." In JOURNAL OF NUCLEAR MEDICINE, vol. 42, no. 5, pp. 64P-64P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2001.
18. Chumpradit, S., S. R. Choi, Z‐P. Zhuang, and H. F. Kung. "A novel iodinated benzamide derivative for imaging endogenous dopamine." Journal of Labelled Compounds and Radiopharmaceuticals 44, no. S1 (2001): S225-S227.
19. Chumpradit, S., S. R. Choi, C. Hou, P. D. Acton, and H. F. Kung. "Novel TC‐99M N2S2 derivatives for imaging 5HT2A receptors." Journal of Labelled Compounds and Radiopharmaceuticals 44, no. S1 (2001): S524-S526.
20. Huang, Y., et al. "Derivation of 5-ht transporter parameters with (11) CDASB and (11) CADAM in baboons: Comparison with 11CMcN5652." Journal of Nuclear Medicine. Vol. 42. No. 5. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2001.
21. Kung, H. F. "Technetium-based SPECT imaging: Application to movement disorder." European Neuropsychopharmacology 11 (2001): S123-S124.
22. Kung, M. P., Z. P. Zhuang, D. M. Skovronsky, C. Hou, B. Zhang, V. M. Y. Lee, J. Q. Trojanowski, and H. F. Kung. "Probes for amyloid plaques in Alzheimer's disease." In NEUROBIOLOGY OF AGING, vol. 22, no. 2, pp. 335-335. 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010 USA: ELSEVIER SCIENCE INC, 2001.
23. Oya, S., S‐R. Choi, C. Hou, M‐P. Kung, P. D. Acton, C‐Y. Shiue, and H. F. Kung. "Synthesis and characterization of 18F‐IDAM as a pet imaging agent for serotonin transporters." Journal of Labelled Compounds and Radiopharmaceuticals44, no. S1 (2001): S15-S17.
24. Skovronsky, D. M., M. P. Kung, B. Zhang, H. Kung, J. Q. Trojanowski, and V. M. Y. Lee. "Development of radioligands for in vivo imaging of brain amyloid." In FASEB JOURNAL, vol. 15, no. 4, pp. A391-A391. 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA: FEDERATION AMER SOC EXP BIOL, 2001.
2000
1. Acton PD, Meyer PT, Mozley PD, Plössl K, Kung HF. Simplified quantification of dopamine transporters in humans using [99mTc]TRODAT-1 and single-photon emission tomography. Eur J Nucl Med. 2000 Nov;27(11):1714-8. doi: 10.1007/s002590000371. PMID: 11105829.
2. Choi SR, Hou C, Oya S, Mu M, Kung MP, Siciliano M, Acton PD, Kung HF. Selective in vitro and in vivo binding of [(125)I]ADAM to serotonin transporters in rat brain. Synapse. 2000 Dec 15;38(4):403-12. doi: 10.1002/1098-2396(20001215)38:4<403::aid-syn5>3.0.CO;2-Z. PMID: 11044887.
3. Dresel S, Krause J, Krause KH, LaFougere C, Brinkbäumer K, Kung HF, Hahn K, Tatsch K. Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment. Eur J Nucl Med. 2000 Oct;27(10):1518-24. doi: 10.1007/s002590000330. PMID: 11083541.
4. Krause KH, Dresel SH, Krause J, Kung HF, Tatsch K. Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography. Neurosci Lett. 2000 May 12;285(2):107-10. doi: 10.1016/s0304-3940(00)01040-5. PMID: 10793238.
5. Krause, J., S. Dresel, K-H. Krause, K. Tatsch, and H. F. Kung. "Reduction of increased striatal dopamine transporter density in adults with attention deficit hyperactivity disorder under methylphenidate—a study with Tc-99m-TRODAT-1-SPECT." European Neuropsychopharmacology 10 (2000): 387-388.
6. Kung, M. P., Z. P. Zhuang, C. Hou, D. Skovronsky, T. Gur, S. Chumpradit, V. M. Y. Lee, J. Q. Trojanowski, and H. F. Kung. "Novel beta amyloid probes." Drug discovery and development for Alzheimer’s disease. Berlin: Springer (2000): 50-6.
7. Mozley PD, Schneider JS, Acton PD, Plössl K, Stern MB, Siderowf A, Leopold NA, Li PY, Alavi A, Kung HF. Binding of [99mTc]TRODAT-1 to dopamine transporters in patients with Parkinson's disease and in healthy volunteers. J Nucl Med. 2000 Apr;41(4):584-9. PMID: 10768556.
8. Oya S, Choi SR, Hou C, Mu M, Kung MP, Acton PD, Siciliano M, Kung HF. 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand. Nucl Med Biol. 2000 Apr;27(3):249-54. doi: 10.1016/s0969-8051(00)00084-6. PMID: 10832081.
9. Skovronsky DM, Zhang B, Kung MP, Kung HF, Trojanowski JQ, Lee VM. In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7609-14. doi: 10.1073/pnas.97.13.7609. PMID: 10861023; PMCID: PMC16593.
10. Stanwood GD, Artymyshyn RP, Kung MP, Kung HF, Lucki I, McGonigle P. Quantitative autoradiographic mapping of rat brain dopamine D3 binding with [(125)I]7-OH-PIPAT: evidence for the presence of D3 receptors on dopaminergic and nondopaminergic cell bodies and terminals. J Pharmacol Exp Ther. 2000 Dec;295(3):1223-31. PMID: 11082459.
11. Zhuang Z, Choi S, Hou C, Mu M, Kung M, Acton PD, Kung HF. A novel serotonin transporter ligand: (5-iodo-2-(2-dimethylaminomethylphenoxy)-benzyl alcohol. Nucl Med Biol. 2000 Feb;27(2):169-75. doi: 10.1016/s0969-8051(99)00093-1. PMID: 10773546.
12. Acton, P. D., M. Mu, C. Hou, M. Siciliano, J. Lupo, S. Oya, Z. P. Zhuang et al. "Comparison of three selective serotonin transporter radioligands for SPECT." In Journal of Nuclear Medicine, vol. 41, no. 5, pp. 39P-39P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
13. Alavi, A. A., P. D. Mozley, and H. F. Kung. "SPECT measurements of dopamine transporters patients with Parkinson's disease and healthy human volunteers: Comparison of [Tc-99m] TRODAT-1 with [I-123] Altropane." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 222P-222P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
14. Choi, S. R., M. P. Kung, M. Mu, C. Hou, S. Oya, P. D. Acton, and H. F. Kung. "Characterization of ADAM: An improved serotonin transporter imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 241P-241P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
15. Choi, S. R., S. Chumpradit, M. P. Kung, and H. F. Kung. "Novel iodinated nucleoside as a potential tumor imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 233P-234P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
16. Chumpradit, S., M. P. Kung, M. Mu, M. Siciliano, and H. F. Kung. "Novel iodinated 7-benzamido-1-(4-methyl-1-piperazinyl)-naphthalenes as potential 5-HT1A receptor imaging agents." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 220, pp. U556-U557. 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC, 2000.
17. Dresel, S., K. H. Krause, J. Krause, H. F. Kung, K. Hahn, and K. Tatsch. "Attention deficit hyperactivity disorder: Assessment of the dopamine transporter before and after methylphenidate treatment as measured by [Tc-99m] TRODAT-1." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 27P-27P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
18. MacDonald, L. R., J. S. Iwanczyk, B. E. Patt, C. R. Tull, P. D. Acton, H. F. Kung, and B. M. W. Tsui. "Development of new high resolution detectors for small animal SPECT imaging." In 2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No. 00CH37149), vol. 3, pp. 21-75. IEEE, 2000.
19. Meyer, P. T., P. D. Mozley, P. D. Acton, J. Ramsey, K. Plossl, A. A. Alavi, and H. F. Kung. "Influence of nonspecific factors on measurements of dopamine transporters with [Tc-99m] TRODAT-1." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 221P-222P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
20. Mozley, L. M. H., P. D. Mozley, J. S. Schneider, A. Siderowf, M. B. Stern, K. Plossl, P. D. Acton et al. "Dopamine transporter pathophysiology in Parkinson's disease. Relationships between the uptake of [Tc-99m] TRODAT-1 and symptom severity." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 137P-137P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
21. Oya, S. I., S. R. Choi, C. Hou, M. P. Kung, C. Y. Shiue, and H. F. Kung. "Novel fluorinated serotonin transporter imaging agents." In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 220, pp. U556-U556. 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC, 2000.
22. Oya, S., S. R. Choi, C. Hou, M. Mu, M. P. Kung, P. D. Acton, and H. F. Kung. "ADAM: An improved serotonin transporter ligand." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 241P-241P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
23. Shiue, C., G. G. Shiue, P. A. Nowak, S. Oya, S. R. Choi, and H. F. Kung. "5-Iodo-2-[[2, 2-[([11C] dimethyl-amino) methyl] phenyl] thio] benzyl alcohol (N-[11C] IDAM): A new serotonin re-uptake sites tracer for PET studies." J. Nucl. Med 41 (2000) 241
24. Yang, B., L. Wu, C. S. Day, K. T. Wheeler, S. R. Choi, H. F. Kung, and R. H. Mach. "A sigma-2 selective Tc-99m compound as a potential tumor imaging agent." In JOURNAL OF NUCLEAR MEDICINE, vol. 41, no. 5, pp. 121P-121P. 1850 SAMUEL MORSE DR, RESTON, VA 20190-5316 USA: SOC NUCLEAR MEDICINE INC, 2000.
